| Cat. No. |
Product Name |
Information |
| PC-61953 |
BPR1K653
Aurora A/B inhibitor
|
BPR1K653 is a novel potent Aurora kinase inhibitor that inhibits Aurora-A and Aurora-B with IC50 of 24 nM and 45 nM, respectively. |
| PC-61353 |
AKI-603
Aurora A inhibitor
|
A novel small molecule Aurora A kinase inhibitor with IC50 of 12.3 nM, also inhibits Aurora B kinase activity to a less extent. |
| PC-61195 |
BRD-7880
Aurora B/C inhibitor
|
BRD-7880 (BRD7880) potent and highly specific inhibitor of Aurora B and Aurora C with IC50 of 7 and 12 nM respectively, with less activity against Aurora A (IC50>2 uM). |
| PC-61110 |
SA16
PDK1/Aurora A inhibitor
|
SA16 is a potent, dual PDK1 and Aurora kinase A inhibitor with IC50 of 416 and 35 nM, respectively. |
| PC-60347 |
AKCI
AURKC-IκBα inhibitor
|
AKCI is a small-molecule inhibitor that blocks the Aurora C/IκBα interaction (IC50=24.9 uM) and exerts antitumor activity in MDA-MB-231 breast cancer cells. |
| PC-42424 |
MLN8054
Aurora A inhibitor
|
MLN8054 is a potent, selective, ATP-competitive, orally active Aurora A kinase inhibitor with IC50 of 4 nM. |
| PC-45943 |
GSK1070916
Aurora B/C inhibitor
|
GSK1070916 is a potent, selective and ATP-competitive inhibitor of Aurora B and Aurora C with Ki of 0.38 nM and 1.5 nM, respectively. |
| PC-42612 |
SCH-1473759 hydrochloride
Aurora A/B inhibitor
|
SCH-1473759 hydrochloride is a potent, picomolar, dual inhibitor of Aurora A and Aurora B with IC50 of 0.02 and 0.03 nM, respectively. |
| PC-42611 |
SCH-1473759
Aurora A/B inhibitor
|
SCH-1473759 is a potent, picomolar, dual inhibitor of Aurora A and Aurora B with IC50 of 0.02 and 0.03 nM, respectively. |
| PC-42703 |
CCT 137690
Aurora Kinase inhibitor
|
CCT 137690 is a potent, orally bioavailable Aurora kinases inhibitor with IC50 of 15/25/19 nM for Aurora A/B/C, respectively. |
| PC-42420 |
PHA-680632
Aurora Kinase inhibitor
|
PHA-680632 is a potent, highly selective Aurora kinase inhibitor with IC50 of 27, 135 and 120 nM for Aurora A, B and C, respectively. |
| PC-42342 |
Barasertib
AURKB inhibitor
|
Barasertib (AZD1152) is a potent, highly selective Aurora B inhibitor with IC50 of 0.37 nM. |
