| Cat. No. |
Product Name |
Information |
| PC-42611 |
SCH-1473759
Aurora A/B inhibitor
|
SCH-1473759 is a potent, picomolar, dual inhibitor of Aurora A and Aurora B with IC50 of 0.02 and 0.03 nM, respectively. |
| PC-42703 |
CCT 137690
Aurora Kinase inhibitor
|
CCT 137690 is a potent, orally bioavailable Aurora kinases inhibitor with IC50 of 15/25/19 nM for Aurora A/B/C, respectively. |
| PC-42420 |
PHA-680632
Aurora Kinase inhibitor
|
PHA-680632 is a potent, highly selective Aurora kinase inhibitor with IC50 of 27, 135 and 120 nM for Aurora A, B and C, respectively. |
| PC-42342 |
Barasertib
AURKB inhibitor
|
Barasertib (AZD1152) is a potent, highly selective Aurora B inhibitor with IC50 of 0.37 nM. |
| PC-42422 |
Danusertib
Aurora kinases inhibitor
|
Danusertib (PHA-739358) is a potent, ATP-competitive Aurora kinase inhibitor with IC50 of 13,79 and 61 nM for Aurora A, B and C, respectively. |
| PC-42650 |
CYC-116
Aurora A/B inhibitor
|
CYC-116 is a potent and selective Aurora A/Aurora B inhibitor with IC50 of 8.0/9.2 nM. |
| PC-42757 |
Alisertib
Aurora A inhibitor
|
Alisertib (MLN8237) is a potent and highly selective inhibitor of Aurora A (AURKA) with IC50 of 1.2 nM. |
| PC-45829 |
AT-9283
Aurora kinases inhibitor
|
AT-9283 is a multi-targeted kinase inhibitor with potent activity against Aurora A, Aurora B, JAK2, JAK3, and ABL (T315I) with IC50 of 3, 3, 1.2, 1.1, and 4 nM, respectively. |
| PC-42766 |
ENMD-2076
Multikinase inhibitor
|
ENMD-2076 is a multitargeted kinase inhibitor with IC50s of 3/14/23/40 nM for Flt3/Aurora A/Src/VEGFR2, respectively. |
| PC-42912 |
TAK-901
Multikinase inhibitor
|
TAK-901 is a multikinase inhibitor with IC50 of 21 nM and 15 nM for Aurora A/TPX2 and Aurora B/INCENP respectively. |
| PC-42409 |
Tozasertib
Aurora kinases inhibitor
|
Tozasertib (MK-0457, VX-680) is a highly potent, selective and reversible Aurora kinase inhibitor with Ki of 0.6, 18 and 4.6 nM for Aurora A, B and C, respectively. |
| PC-22957 |
CAM2602
Aurora A-TPX2 inhibitor
|
CAM2602 is a potent, selective small molecule inhibitor of Aurora A-TPX2 protein-protein interaction (PPI), binds to Aurora A and displaces TPX2 from Aurora A with a KD of 19 nM, |
