| Cat. No. |
Product Name |
Information |
| PC-22139 |
6K465
Aurora A inhibitor
|
6K465 is a potent selective Aurora A (AURKA) inhibitor, effectively inhibits cancer cells overexpressing c-MYC- and/or N-MYC. |
| PC-21560 |
Reversine
Aurora Kinase inhibitor
|
Reversine is a potent, ATP-competitive Aurora kinases inhibitor with IC50 of 400, 500 and 400 nM for Aurora A, Aurora B and Aurora C, respectively. |
| PC-21147 |
Ilorasertib
Aurora Kinase inhibitor
|
Ilorasertib (ABT-348) is a potent inhibitor of Aurora kinases as well as the VEGF and PDGF families of receptor tyrosine kinases (Aur B IC50=2 nM, PDGFRβ IC50=3 nM). |
| PC-49273 |
PF-03814735
Aurora inhibitor
|
PF-03814735 is a potent, orally bioavailable, reversible inhibitor of both Aurora A and Aurora B kinases with IC50 values of 0.8 and 5 nM, respectively. |
| PC-73448 |
Tinengotinib
Multikinase inhibitor
|
Tinengotinib (TT-00420) is a spectrum-selective multikinase inhibitor that targets cell proliferation, angiogenesis, and immunomodulatory pathways by inhibiting Aurora A/B and JAK involved in cytokine signalling, and RTKs involved in angiogenesis (FGFRs and VEGFRs). |
| PC-42340 |
AZD1152-HQPA
|
The active product of AZD1152, a potent, selective inhibitor of Aurora B kinase with IC50 of 0.37 nM. |
| PC-45948 |
Aurora A-IN-10
|
A potent, highly selective Aurora A inhibitor with IC50 of 3.4 nM. |
| PC-42765 |
ENMD-2076 tartrate
|
A multitargeted kinase inhibitor with IC50s of 3/14/23/40 nM for Flt3/Aurora A/Src/VEGFR2. |
