| Cat. No. |
Product Name |
Information |
| PC-42342 |
Barasertib
Aurora B inhibitor
|
Barasertib (AZD1152) is a potent, highly selective Aurora B inhibitor with IC50 of 0.37 nM. |
| PC-45948 |
TCS7010
Aurora A inhibitor
|
TCS7010 is a potent, highly selective Aurora A inhibitor with IC50 of 3.4 nM. |
| PC-42422 |
Danusertib
Aurora kinase inhibitor
|
Danusertib (PHA-739358) is a potent, ATP-competitive Aurora kinase inhibitor with IC50 of 13,79 and 61 nM for Aurora A, B and C, respectively. |
| PC-42650 |
CYC-116
Aurora A/B inhibitor
|
CYC-116 (CYC116) is a potent and selective Aurora A/Aurora B inhibitor with IC50 of 8.0/9.2 nM. |
| PC-42757 |
Alisertib
Aurora A inhibitor
|
Alisertib (MLN8237) is a potent and highly selective inhibitor of Aurora A (AURKA) with IC50 of 1.2 nM. |
| PC-45829 |
AT9283
Aurora/JAK inhibitor
|
AT-9283 (AT9283) is a multi-targeted kinase inhibitor with potent activity against Aurora A, Aurora B, JAK2, JAK3, and ABL (T315I) with IC50 of 3, 3, 1.2, 1.1, and 4 nM, respectively. |
| PC-42766 |
ENMD-2076
Multikinase inhibitor
|
ENMD-2076 is a multitargeted kinase inhibitor with IC50s of 3/14/23/40 nM for Flt3/Aurora A/Src/VEGFR2, respectively. |
| PC-42765 |
ENMD-2076 tartrate
Multikinase inhibitor
|
ENMD-2076 tartrate is a multitargeted kinase inhibitor with IC50s of 3/14/23/40 nM for Flt3/Aurora A/Src/VEGFR2; also inhibits Aurora B, c-Kit, FGFR1 (IC50=100-350 nM); orally bioactive. |
| PC-42912 |
TAK-901
Multikinase inhibitor
|
TAK-901 is a multikinase inhibitor with IC50 of 21 nM and 15 nM for Aurora A/TPX2 and Aurora B/INCENP respectively. |
| PC-42409 |
Tozasertib
Aurora kinases inhibitor
|
Tozasertib (MK-0457, VX-680) is a highly potent, selective and reversible Aurora kinase inhibitor with Ki of 0.6, 18 and 4.6 nM for Aurora A, B and C, respectively. |
| PC-26261 |
NN-01-195
HSP90/AURKA inhibitor
|
NN-01-195 is a chimeric small molecule conjugate of HSP90 and AURKA inhibitor, tightly binds and inhibits both AURKA and HSP90 with IC50 of 3.1 nM and 8.1 nM in biochemical assays. |
| PC-22459 |
AurkinA
Aurora A inhibitor
|
AurkinA (Aurkin A) is a chemical inhibitor of the AURKA-TPX2 interaction and potent allosteric inhibitor of Aurora A (AURKA), shows binding affinity to AURKA with ITC Kd of 3.77 uM. |
