| Cat. No. |
Product Name |
Information |
| PC-20713 |
LXY18
AURKB inhibitor
|
LXY18 is a potent orally available blocker of AURKB relocation in mitosis with minimum effective concentration (MEC) of 3.5 nM for inducing polyploidy, shows broad-spectrum growth inhibitory and apoptosis-inducing activities with low nanomolar potencies. |
| PC-49273 |
PF-03814735
Aurora inhibitor
|
PF-03814735 is a potent, orally bioavailable, reversible inhibitor of both Aurora A and Aurora B kinases with IC50 values of 0.8 and 5 nM, respectively. |
| PC-38795 |
PHA-680626
Aurora Kinase inhibitor
|
PHA-680626 is a kinase inhibitor exhibiting strong inhibitory activity on both Bcr-Abl and Aurora kinases, also inhibits the formation of the Aurora-A/N-Myc complex. |
| PC-73448 |
Tinengotinib
Multikinase inhibitor
|
Tinengotinib (TT-00420) is a spectrum-selective multikinase inhibitor that targets cell proliferation, angiogenesis, and immunomodulatory pathways by inhibiting Aurora A/B and JAK involved in cytokine signalling, and RTKs involved in angiogenesis (FGFRs and VEGFRs). |
| PC-42340 |
AZD1152-HQPA
|
The active product of AZD1152, a potent, selective inhibitor of Aurora B kinase with IC50 of 0.37 nM. |
| PC-45948 |
Aurora A-IN-10
|
A potent, highly selective Aurora A inhibitor with IC50 of 3.4 nM. |
| PC-42765 |
ENMD-2076 tartrate
|
A multitargeted kinase inhibitor with IC50s of 3/14/23/40 nM for Flt3/Aurora A/Src/VEGFR2. |
