Cat. No. |
Product Name |
Information |
PC-21321 |
KIN-3248
FGFR inhibitor
|
Resigratinib (KIN-3248) is a next-generation, irreversible, orally available, small molecule pan-FGFR inhibitor with IC50 of 3.9/5.3/9.7 nM for FGFR1/2/3, potently inhibits FGFR2 and FGFR3 gatekeeper, molecular brake, and activation loop mutations with IC50 of 5-20 nM. |
PC-35145 |
E7090 succinate
|
E7090 (E 7090) is a potent, selective, orally available inhibitor of FGFR1, -2, and -3 with IC50 of 0.71, 0.50 and 1.2 nM, weakly inhibits FGFR4 (IC50=120 nM). |
PC-45475 |
FIIN-3
|
A selective, next-generation, covalent dual FGFR/EGFR inhibitor (IC50=1-60 nM). |
PC-42567 |
SU 5402
|
A selective FGFR1 inhibitor with IC50 of 10-20 uM. |
PC-42217 |
FGFR4-IN-1
|
A potent, selective inhibiotr of FGFR4 with IC50 of 0.7 nM, significantly inhibits the proliferation of HuH-7 cells with IC50 of 7.8 nM.. |