FGFR (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-42452	Dovitinib lactate Multikinase inhibitor	Dovitinib lactate (CHIR-258, TKI-258) is a multitargeted RTK inhibitor of class III, IV, and V RTKs with IC50 of 1/2/36/8/9 nM for FLT3/c-KIT/c-Fms/FGFR1/FGFR3, respectively.
PC-42173	BLU-554 FGFR4 inhibitor	BLU-554 (Fisogatinib, BLU554) is a novel potent, highly selective and orally bioavailable inhibitor of FGFR4 with IC50 of 5 nM.
PC-42401	SUN11602 bFGF mimic	A novel aniline compound that mimics the neuroprotective effects of bFGF by activating FGFR1-MEK/ERK signaling pathway.
PC-45537	Erdafitinib FGFR inhibitor	Erdafitinib (JNJ-42756493) is a highly potent and selective, small-molecule inhibitor of FGFR family with IC50s of 1.2/2.5/3/5.7 nM for FGFR1/2/3/4.
PC-42406	FGF-401 FGFR4 inhibitor	FGF-401 (NVP-FGF401, Roblitinib, FGF401) is a first-in-class, potent, highly selective FGFR4 inhibitor with IC50 of 1.1 nM.
PC-25243	TCB-32 bFGF mimic, FGFR1 activator	TCB-32 is an agonistic small molecules that mimic binding of basic fibroblast growth factor (bFGF), shows a strong proliferative effect in NIH 3T3 cells, activates the same FGFR1-signaling pathway as bFGF.
PC-22625	FGF trap compound 57 FGF trap inhibitor	FGF trap compound 57 is a non-steroidal NSC12 derivative as FGF trap small molecule, shows anti-myeloma activity.

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