FGFR (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-45537	Erdafitinib FGFR inhibitor	Erdafitinib (JNJ-42756493) is a highly potent and selective, small-molecule inhibitor of FGFR family with IC50s of 1.2/2.5/3/5.7 nM for FGFR1/2/3/4.
PC-42406	FGF-401 FGFR4 inhibitor	FGF-401 (NVP-FGF401, Roblitinib, FGF401) is a first-in-class, potent, highly selective FGFR4 inhibitor with IC50 of 1.1 nM.
PC-25243	TCB-32 bFGF mimic, FGFR1 activator	TCB-32 is an agonistic small molecules that mimic binding of basic fibroblast growth factor (bFGF), shows a strong proliferative effect in NIH 3T3 cells, activates the same FGFR1-signaling pathway as bFGF.
PC-24894	INCB126503 FGFR2/3 inhibitor	INCB126503 is a highly potent, selective, orally bioavailable FGFR2/3 inhibitor with IC50 of 2.1/1.2 nM respectively.
PC-24856	ISM7594 FGFR2/3 inhibitor	ISM7594 is a potent, selective and covalent FGFR2/3 inhibitor with IC50 of 1.4/12.7 nM respectively, inhibits FGFR2 mutants and FGFR3 mutants with IC50 of 0.22-5.9 nM and 3.7-26 nM, selectively spares FGFR1/4.
PC-22625	FGF trap compound 57 FGF trap inhibitor	FGF trap compound 57 is a non-steroidal NSC12 derivative as FGF trap small molecule, shows anti-myeloma activity.

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