FGFR (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-21321	KIN-3248 FGFR inhibitor	Resigratinib (KIN-3248) is a next-generation, irreversible, orally available, small molecule pan-FGFR inhibitor with IC50 of 3.9/5.3/9.7 nM for FGFR1/2/3, potently inhibits FGFR2 and FGFR3 gatekeeper, molecular brake, and activation loop mutations with IC50 of 5-20 nM.
PC-35145	E7090 succinate	E7090 (E 7090) is a potent, selective, orally available inhibitor of FGFR1, -2, and -3 with IC50 of 0.71, 0.50 and 1.2 nM, weakly inhibits FGFR4 (IC50=120 nM).
PC-45475	FIIN-3	A selective, next-generation, covalent dual FGFR/EGFR inhibitor (IC50=1-60 nM).
PC-42567	SU 5402	A selective FGFR1 inhibitor with IC50 of 10-20 uM.
PC-42217	FGFR4-IN-1	A potent, selective inhibiotr of FGFR4 with IC50 of 0.7 nM, significantly inhibits the proliferation of HuH-7 cells with IC50 of 7.8 nM..

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