| Cat. No. |
Product Name |
Information |
| PC-70221 |
ASP-5878
|
ASP-5878 (ASP5878) is a novel potent, selective pan-FGFR inhibitor with IC50 of 0.47/0.60/0.74/3.5 nM for FGFR1/2/3/4, respectively. |
| PC-60465 |
MPT0L145
PIK3C3/FGFR inhibitor
|
MPT0L145 is a nove potent, dual FGFR and PIK3C3 inhibitor with Kd of 0.53 nM for PIK3C3. |
| PC-60073 |
PRN-1371
FGFR inhibitor
|
PRN-1371 (PRN1371) is a potent, selective, irreversible covalent, orally active pan-FGFR inhibitor with IC50 of 0.6/1.3/4.1/19.3 nM for FGFR1/2/3/4, respectively. |
| PC-60038 |
Derazantinib
FGFR inhibitor
|
Derazantinib (ARQ-087) is a novel potent, ATP competitive multi-kinase inhibitor with IC50 of FGFR1/2/3 with IC50 of 1.8-4.5 nM. |
| PC-45474 |
FIIN-2
FGFR inhibitor
|
FIIN-2 is a potent, irreversible inhibitor of FGFR with IC50 values of 3.1/ 4.3/27/45 nM for FGFR1/2/3/4. |
| PC-42521 |
PD173074
FGFR1 inhibitor
|
PD173074 is a potent, selective, ATP-competitive FGFR1 inhibitor with IC50 of ~25 nM. |
| PC-45761 |
CH-5183284
|
CH-5183284 (Debio-1347, Debio1347) is a potent, selective and orally available FGFR1/2/3 inhibitor with enzyme IC50 of 9.3/7.6/22 nM, respectively. |
| PC-43499 |
AZD4547
FGFR inhibitor
|
AZD4547 (ADSK091) is a potent and selective inhibitor of FGFR1/2/3 with IC50s of 0.2/1.8/2.5 nM, respectively. |
| PC-42173 |
BLU-554
|
BLU-554 (Fisogatinib, BLU554) is a novel potent, highly selective and orally bioavailable inhibitor of FGFR4 designed for hepatocellular carcinoma (HCC) with FGFR4 pathway activation. |
| PC-45537 |
Erdafitinib
FGFR inhibitor
|
Erdafitinib (JNJ-42756493) is a highly potent and selective, small-molecule inhibitor of FGFR family with IC50s of 1.2/2.5/3/5.7 nM for FGFR1/2/3/4. |
| PC-42406 |
FGF-401
|
FGF-401 (NVP-FGF401, Roblitinib, FGF401) is a first-in-class, potent, highly selective FGFR4 inhibitor with IC50 of 1.1 nM. |
| PC-21612 |
DW14383
FGFR inhibitor
|
DW14383 is a potent, selective and irreversible inhibitor of FGFR1-4 with IC50 of <0.3 nM, 1.1 nM, <0.3 nM and 0.5 nM for FGFR1/2/3/4 respectively. |
