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Cat. No. Product Name Information
PC-43499

AZD4547

FGFR inhibitor

Fexagratinib (AZD4547, ADSK091) is a potent and selective inhibitor of FGFR1/2/3 with IC50s of 0.2/1.8/2.5 nM, respectively.
PC-45899

Dovitinib

Multikinase inhibitor

Dovitinib (CHIR-258, TKI258) is a multitargeted RTK inhibitor of class III, IV, and V RTKs with IC50 of 1/2/36/8/9 nM for FLT3/c-KIT/c-Fms/FGFR1/FGFR3, respectively.
PC-42452

Dovitinib lactate

Multikinase inhibitor

Dovitinib lactate (CHIR-258, TKI-258) is a multitargeted RTK inhibitor of class III, IV, and V RTKs with IC50 of 1/2/36/8/9 nM for FLT3/c-KIT/c-Fms/FGFR1/FGFR3, respectively.
PC-42173

BLU-554

FGFR4 inhibitor

BLU-554 (Fisogatinib, BLU554) is a novel potent, highly selective and orally bioavailable inhibitor of FGFR4 with IC50 of 5 nM.
PC-42401

SUN11602

bFGF mimic

A novel aniline compound that mimics the neuroprotective effects of bFGF by activating FGFR1-MEK/ERK signaling pathway.
PC-45537

Erdafitinib

FGFR inhibitor

Erdafitinib (JNJ-42756493) is a highly potent and selective, small-molecule inhibitor of FGFR family with IC50s of 1.2/2.5/3/5.7 nM for FGFR1/2/3/4.
PC-42406

FGF-401

FGFR4 inhibitor

FGF-401 (NVP-FGF401, Roblitinib, FGF401) is a first-in-class, potent, highly selective FGFR4 inhibitor with IC50 of 1.1 nM.
PC-24894

INCB126503

FGFR2/3 inhibitor

INCB126503 is a highly potent, selective, orally bioavailable FGFR2/3 inhibitor with IC50 of 2.1/1.2 nM respectively.
PC-24856

ISM7594

FGFR2/3 inhibitor

ISM7594 is a potent, selective and covalent FGFR2/3 inhibitor with IC50 of 1.4/12.7 nM respectively, inhibits FGFR2 mutants and FGFR3 mutants with IC50 of 0.22-5.9 nM and 3.7-26 nM, selectively spares FGFR1/4.
PC-24068

BW710

FGFR2 inhibitor

BW710 is a potent, selective, covalent and orally bioavailable FGFR2 inhibitor, potently inhibits the proliferation of BaF3-FGFR2 cells with IC50 of 2.8 nM.
PC-22684

SSR128129E

FGFR inhibitor

SSR128129E is a specific, allosteric, small-molecule multi-FGF receptor (FGFR) inhibitor, binds to the extracellular FGFR domain without affecting orthosteric FGF binding.
PC-22625

FGF trap compound 57

FGF trap inhibitor

FGF trap compound 57 is a non-steroidal NSC12 derivative as FGF trap small molecule, shows anti-myeloma activity.

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