| Cat. No. |
Product Name |
Information |
| PC-43499 |
AZD4547
FGFR inhibitor
|
Fexagratinib (AZD4547, ADSK091) is a potent and selective inhibitor of FGFR1/2/3 with IC50s of 0.2/1.8/2.5 nM, respectively. |
| PC-45899 |
Dovitinib
Multikinase inhibitor
|
Dovitinib (CHIR-258, TKI258) is a multitargeted RTK inhibitor of class III, IV, and V RTKs with IC50 of 1/2/36/8/9 nM for FLT3/c-KIT/c-Fms/FGFR1/FGFR3, respectively. |
| PC-42452 |
Dovitinib lactate
Multikinase inhibitor
|
Dovitinib lactate (CHIR-258, TKI-258) is a multitargeted RTK inhibitor of class III, IV, and V RTKs with IC50 of 1/2/36/8/9 nM for FLT3/c-KIT/c-Fms/FGFR1/FGFR3, respectively. |
| PC-42173 |
BLU-554
FGFR4 inhibitor
|
BLU-554 (Fisogatinib, BLU554) is a novel potent, highly selective and orally bioavailable inhibitor of FGFR4 with IC50 of 5 nM. |
| PC-42401 |
SUN11602
bFGF mimic
|
A novel aniline compound that mimics the neuroprotective effects of bFGF by activating FGFR1-MEK/ERK signaling pathway. |
| PC-45537 |
Erdafitinib
FGFR inhibitor
|
Erdafitinib (JNJ-42756493) is a highly potent and selective, small-molecule inhibitor of FGFR family with IC50s of 1.2/2.5/3/5.7 nM for FGFR1/2/3/4. |
| PC-42406 |
FGF-401
FGFR4 inhibitor
|
FGF-401 (NVP-FGF401, Roblitinib, FGF401) is a first-in-class, potent, highly selective FGFR4 inhibitor with IC50 of 1.1 nM. |
| PC-24894 |
INCB126503
FGFR2/3 inhibitor
|
INCB126503 is a highly potent, selective, orally bioavailable FGFR2/3 inhibitor with IC50 of 2.1/1.2 nM respectively. |
| PC-24856 |
ISM7594
FGFR2/3 inhibitor
|
ISM7594 is a potent, selective and covalent FGFR2/3 inhibitor with IC50 of 1.4/12.7 nM respectively, inhibits FGFR2 mutants and FGFR3 mutants with IC50 of 0.22-5.9 nM and 3.7-26 nM, selectively spares FGFR1/4. |
| PC-24068 |
BW710
FGFR2 inhibitor
|
BW710 is a potent, selective, covalent and orally bioavailable FGFR2 inhibitor, potently inhibits the proliferation of BaF3-FGFR2 cells with IC50 of 2.8 nM. |
| PC-22684 |
SSR128129E
FGFR inhibitor
|
SSR128129E is a specific, allosteric, small-molecule multi-FGF receptor (FGFR) inhibitor, binds to the extracellular FGFR domain without affecting orthosteric FGF binding. |
| PC-22625 |
FGF trap compound 57
FGF trap inhibitor
|
FGF trap compound 57 is a non-steroidal NSC12 derivative as FGF trap small molecule, shows anti-myeloma activity. |
