| Cat. No. |
Product Name |
Information |
| PC-42401 |
SUN11602
bFGF mimic
|
A novel aniline compound that mimics the neuroprotective effects of bFGF by activating FGFR1-MEK/ERK signaling pathway. |
| PC-45537 |
Erdafitinib
FGFR inhibitor
|
Erdafitinib (JNJ-42756493) is a highly potent and selective, small-molecule inhibitor of FGFR family with IC50s of 1.2/2.5/3/5.7 nM for FGFR1/2/3/4. |
| PC-42406 |
FGF-401
FGFR4 inhibitor
|
FGF-401 (NVP-FGF401, Roblitinib, FGF401) is a first-in-class, potent, highly selective FGFR4 inhibitor with IC50 of 1.1 nM. |
| PC-22684 |
SSR128129E
FGFR inhibitor
|
SSR128129E is a specific, allosteric, small-molecule multi-FGF receptor (FGFR) inhibitor, binds to the extracellular FGFR domain without affecting orthosteric FGF binding. |
| PC-22625 |
FGF trap compound 57
FGF trap inhibitor
|
FGF trap compound 57 is a non-steroidal NSC12 derivative as FGF trap small molecule, shows anti-myeloma activity. |
| PC-22316 |
LHQ490
FGFR2 inhibitor
|
LHQ490 is a potent, highly selective fibroblast growth factor receptor 2 (FGFR2) inhibitor with Ic50 of 5.2 nM, >61-, >34-, and >293-fold selective against FGFR1, FGFR3, and FGFR4. |
| PC-21612 |
DW14383
FGFR inhibitor
|
DW14383 is a potent, selective and irreversible inhibitor of FGFR1-4 with IC50 of <0.3 nM, 1.1 nM, <0.3 nM and 0.5 nM for FGFR1/2/3/4 respectively. |
| PC-21321 |
KIN-3248
FGFR inhibitor
|
Resigratinib (KIN-3248) is a next-generation, irreversible, orally available, small molecule pan-FGFR inhibitor with IC50 of 3.9/5.3/9.7 nM for FGFR1/2/3, potently inhibits FGFR2 and FGFR3 gatekeeper, molecular brake, and activation loop mutations with IC50 of 5-20 nM. |
| PC-35145 |
E7090 succinate
|
E7090 (E 7090) is a potent, selective, orally available inhibitor of FGFR1, -2, and -3 with IC50 of 0.71, 0.50 and 1.2 nM, weakly inhibits FGFR4 (IC50=120 nM). |
| PC-45475 |
FIIN-3
|
A selective, next-generation, covalent dual FGFR/EGFR inhibitor (IC50=1-60 nM). |
| PC-42567 |
SU 5402
|
A selective FGFR1 inhibitor with IC50 of 10-20 uM. |
| PC-42217 |
FGFR4-IN-1
|
A potent, selective inhibiotr of FGFR4 with IC50 of 0.7 nM, significantly inhibits the proliferation of HuH-7 cells with IC50 of 7.8 nM.. |
