| Cat. No. |
Product Name |
Information |
| PC-28092 |
Oxathiapiprolin
OSBP inhibitor
|
Oxathiapiprolin is a piperidinyl thiazole isoxazoline fungicide that targets oxysterol binding protein (OSBP), shows exceptional activity against plant diseases caused by oomycete pathogens. |
| PC-28091 |
Y18501
OSBP inhibitor
|
Y18501 is a smalll molecule oxysterol-binding protein (OSBP) inhibitor, shows strong inhibitory activity against Pseudoperonospora cubensis with EC50 of 0.001-11.785 ug/mL for 159 Ps. cubensis isolates. |
| PC-28055 |
Abafungin
Antifungal
|
Abafungin (BAY-W-6341) is an arylguanidine antifungal compound with potent antifungal activity via inhibiting sterol-C-24 methyltransferase, Abafungin is a potent inhibitor of ergosterol biosynthesis in C. albicans at 0.01-1 mg/L, inhibits specifically the transmethylation of the sterol side chain. |
| PC-27942 |
Ravuconazole
Antifungal
|
Ravuconazole (BMS-207147, ER-30346) is an oral triazole antifungal with broad antifungal spectrum with MIC90 of 0.025 to 0.78 ug/mL, 4 to 32 times more active than itraconazole, fluconazole, and amphotericin B against Candida albicans, Candida parapsilosis, and Candida glabrata. |
| PC-27772 |
FX0685
Antifungal
|
FX0685 is a triazole antifungal agent with potent activity against fluconazole-resistant Candida albicans, shows potent inhibitory activity against fungal cytochrome P450 protein CYP51. |
| PC-27769 |
NT-a9
Antifungal
|
NT-a9 is an analogue of isavuconazole with strong antifungal activities in vitro and in vivo, shows a wide range of activities against several pathogenic fungi in vitro, including Cryptococcus neoformans, Cryptococcus gattii, Candida albicans, Candida krusei, Candida tropicalis, Candida glabrata, and Candida parapsilosis with MICs of 0.002-1 ug/mL. |
| PC-27585 |
Inz-5
Fungal complex III inhibitor
|
Inz-5 is a fungal-specific indazole derivative inhibitor of Candida albicans (C. albicans) complex III (CIII) with IC50 of 24 nM in UQH2:cyt c oxidoreductase assays. |
| PC-27214 |
SYP-14288
Fungicide
|
SYP-14288 is a novel fungicide acts as an uncoupler of oxidative phosphorylation against Phytophthora capsici, inhibits ATP synthesis of the pathogen. |
| PC-26831 |
F2F-202
HDAC6 inhibitor
|
F2F-202 is a a potent and selective histone deacetylase 6 (HDAC6) inhibitor with IC50 of 7.1 nM, shows great selectivity over HDAC1 and selected as a representative of nuclear HDACs (422-fold), shows synergistic activity in combination with the azole antifungal voriconazole. |
| PC-25620 |
Isoxazole 1
CnAcs1 inhibitor
|
Isoxazole 1 is a potent, specific inhibitor of C. neoformans acetyl-CoA synthetase (CnAcs1) with IC50 of 8.6 uM, shows antifungal activity against WT C. neoformans strain H99 with MIC of 2 ug/mL. |
| PC-24659 |
PanK inhibitor MNS
Fungal PanK inhibitor
|
PanK inhibitor MNS is a broad-spectrum antifungal, fungal-selective inhibitor of PanK with IC50 of 1.13 μM and 17.74 μM against CaCab1p and AfPanKp respectively, directly engages and inhibits PanK to block CoA production. |
| PC-24646 |
Tps1 inhibitor 4456dh
Fungal Tps1 inhibitor
|
Tps1 inhibitor 4456dh is a small molecule inhibitor of the fungal first enzyme in the trehalose biosynthesis pathway, trehalose-6-phosphate synthase (Tps1), demonstrates broad-spectrum inhibitory effects against multiple pathogenic fungal species, including Candida and Cryptococcus. |
