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Request The Product List ofGuanylate Cyclase Guanylate Cyclase

Cat. No. Product Name Information
PC-61610

NS 2028

NS 2028 is a potent, specific soluble guanylate cyclase (sGC) inhibitor with IC50 of 30 and 200 nM for basal and NO-stimulated enzymes, respectively.
PC-61609

S-3448

S-3448 is a potent, specific soluble guanylate cyclase (sGC) activator with EC50 of 0.68 uM, preferentially activates the NO-insensitive heme-oxidized form of sGC.
PC-61608

Ataciguat sodium

Ataciguat (HMR-1766) is a potent, specific soluble guanylate cyclase (sGC) activator with EC50 of 0.51 uM, preferentially activates the NO-insensitive heme-oxidized form of sGC.
PC-61607

Ataciguat

Ataciguat (HMR-1766) is a potent, specific soluble guanylate cyclase (sGC) activator with EC50 of 0.51 uM, preferentially activates the NO-insensitive heme-oxidized form of sGC.
PC-61606

Etriciguat

Etriciguat is a novel potent, selective, orally available soluble guanylate cyclase (sGC) stimulator..
PC-60643

BI 703704

A novel potent soluble guanylate cyclase (sGC) activator.
PC-70008

GSK-2181236A

A potent, selective soluble guanylate cyclase (sGC) stimulator that increases sGC activity (cGMP formation) with EC50s of 27 and 25 nM for rat and human sGC, respectively.
PC-45371

Linaclotide

A potent and selective GC-C agonist (Ki=1.23-1.64 nM) that elicits pharmacological effects locally in the gastrointestinal tract.

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