| Cat. No. |
Product Name |
Information |
| PC-73456 |
Zagociguat
sGC activator
|
Zagociguat is a small molecule activitor of soluble guanylate cyclase (sGC), increases nitric oxide (NO) signaling leading to an increase in cyclic guanosine monophosphate production. |
| PC-72560 |
Rat C53 peptide
pGC-B activator
|
Rat C53 peptide (C53, pGC-B activator C53) is a novel potent, selective particulate guanylyl cyclase B (pGC-B) activator, activates pGC-B/cGMP signaling pathway, and enhances cGMP generating actions. |
| PC-72559 |
Human C53 peptide
pGC-B activator
|
Human C53 peptide (C53, pGC-B activator C53) is a novel potent, selective particulate guanylyl cyclase B (pGC-B) activator, activates pGC-B/cGMP signaling pathway, and enhances cGMP generating actions. |
| PC-72558 |
C-type natriuretic peptide
pGC-B activator
|
C-type natriuretic peptide (CNP, pGC-B activator) is the native particulate guanylyl cyclase B receptor (pGC-B) activator. |
| PC-35120 |
MGV354 R-form
|
MGV354 is a novel potent, selective soluble Guanylate Cyclase (sGC) activator, lowers intraocular pressure (IOP) in preclinical models of glaucoma.. |
| PC-35119 |
MGV354
|
MGV354 is a novel potent, selective soluble Guanylate Cyclase (sGC) activator, lowers intraocular pressure (IOP) in preclinical models of glaucoma.. |
| PC-43008 |
BAY 41-2272
|
BAY 41-2272 is a potent, NO-independent, orally available soluble guanylate cyclase (sGC) stimulator with IC50 of 0.3 uM (relaxation of preconstricted aortic rings). |
| PC-63138 |
ODQ
|
ODQ (sGC inhibitor ODQ) is a potent, selective, irreversible inhibitor of sGC (soluble guanylyl cyclase). |
| PC-63048 |
BAY 41-8543
|
BAY 41-8543 is an NO-independent sGC (soluble guanylyl cyclase) stimulator, inhibits collagen-mediated aggregation in washed human platelets (IC50=90 nM). |
| PC-63047 |
BAY 60-2770
|
BAY 60-2770 is an NO-independent activator of sGC (soluble guanylyl cyclase) with EC50 of 5.4 nM. |
| PC-62156 |
LY-83583
|
LY-83583 is an inhibitor of soluble guanylate cyclase (sGC) and of cGMP production, inhibits sGC in human platelets with IC50 of 2 uM. |
| PC-62076 |
BPIPP
|
BPIPP is an inhibitor of GC-C (guanylyl cyclase type C) that inhibits stimulation of guanylyl cyclase and adenylyl cyclase, suppresses cGMP accumulation in a variety of cell lines (IC50=3.4-11.2 uM). |
