HBV compound (inhibitors, antagonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-42040	Bay 41-4109 HBV capsid inhibitor	Bay 41-4109 is a potent, non-nucleosidic inhibitor of HBV nucleocapsid maturation with IC50 of 0.05 uM.
PC-23459	AB-161 PAPD5/7 inhibitor	AB-161 is a potent, selective and orally bioavailable PAPD5/7 inhibitor (IC50=0.85/1.1 uM) and HBV RNA destabilizer with EC50 of 2.2 nM for reduction of HBsAg in HepG2.2.15 cells.
PC-22187	GS-6671 HBsAg inhibitor	GS-6671 is a potent, orally bioavailable inhibitor of HBV surface antigen (HBsAg) with EC50 of 5.8 nM in HepG2-NTCP assays, via inhibition of the human poly(A) polymerases PAPD5/7, promoting destabilization and degradation of HBV mRNA.
PC-22186	GS-8873 HBsAg inhibitor	GS-8873 is a potent, orally bioavailable inhibitor of HBV surface antigen (HBsAg) with EC50 of 4 nM in HepG2-NTCP assays, via inhibition of the human poly(A) polymerases PAPD5/7, promoting destabilization and degradation of HBV mRNA.
PC-21261	Alisporivir Cyclophilin inhibitor	Alisporivir (Debio 025, DEBIO-025) is a non-immunosuppressive cyclophilin inhibitor derived from cyclosporin A (CsA) with IC50 of 30 nM (CypD PPIase activity ), inhibits HCV replication in vitro more potently than CsA.

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