| Cat. No. |
Product Name |
Information |
| PC-63406 |
HAP-12
HBV capsid inhibitor
|
HAP-12 is a small molecule HBV capsid assembly effector that inhibits HBV DNA replication with EC50 of 0.5 uM.. |
| PC-63405 |
IR415
HBV X protein inhibitor
|
IR415 is a novel small molecule inhibitor of HBV virus replication that blocks hepatitis B virus X protein (HBx, Kd=2 nM) mediated RNAi suppression, reverses the inhibitory effect of HBx protein on activity of the Dicer endoribonuclease. |
| PC-63404 |
HBV Capsid inhibitor 3711
HBV capsid inhibitor
|
HBV Capsid inhibitor 3711 (Compound 3711) is a nonnucleosidic HBV inhibitor, inhibits hepatitis B virus replication by inducing genome-free capsid formation. |
| PC-63403 |
BCM-599
HBV capsid inhibitor
|
BCM-599 is an efficient HBV capsid assembly inhibitor with in vitro IC50 of 13 uM, shows synergistic inhibitory effects on decreasing viral concentration combined with lamivudine in vivo. |
| PC-63329 |
Isothiafludine
HBV capsid inhibitor
|
Isothiafludine (NZ-4) is a novel HBV capsid assembly inhibitor that inhibits HBV replication through blocking pregenomic RNA encapsidation, suppresses HBV replication in HepG2.2.15 cells with IC50 of 1.33 uM. |
| PC-63328 |
HEC72702
HBV capsid inhibitor
|
HEC72702 is a novel potent, orally active inhibitor of HBV capsid assembly, inhibits HBV-DNA levels in HepG.2.2.15 cells with IC50 of 39 nM. |
| PC-63327 |
AT-130
HBV capsid inhibitor
|
AT-130 is a potent inhibitor of HBV capsid assembly, inhibits wild-type HBV replication with IC50 of 2.4 uM. |
| PC-63326 |
GLS4
HBV capsid inhibitor
|
GLS4 (Morphothiadin) is a potent inhibitor of HBV capsid assembly, inhibits HBV replication (EC50=62.24 nM). |
| PC-63323 |
AB-423
HBV capsid inhibitor
|
AB-423 is a novel potent, class II HBV capsid inhibitor that shows potent inhibition of HBV replication with EC50 of 0.08-0.27 uM, with no significant cytotoxicity (CC50>10 uM). |
| PC-63285 |
Besifovir
HBV inhibitor
|
Besifovir (ANA-380, LB-80380) is a potent, selective, orally available anti-HBV agent, the prodrug of PMCDG (EC50=4 uM). |
| PC-43149 |
Tizoxanide
Antibiotic
|
Tizoxanide is the main metabolite of nitazoxanide, which is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent against anaerobic bacteria, protozoa, and a range of viruses. |
| PC-62578 |
RO6889678
HBV capsid inhibitor
|
RO6889678 is a highly potent inhibitor of HBV capsid formation with attributes that are favorable for targeting the liver, whilst maintaining moderate peripheral exposure. |
