| Cat. No. |
Product Name |
Information |
| PC-21191 |
LQFM215
SLC6A7 inhibitor
|
LQFM215 (LQFM-215) is a synthetic L-proline transporter (PROT/SLC6A7) inhibitor, inhibits proline uptake in hippocampal synaptosome with IC50 of 20.4 uM, present neuroprotective potential. |
| PC-49734 |
RRR-DHTBZ camphorsulfonic acid salt
VMAT2 inhibitor
|
RRR-dihydrotetrabenazine (RRR-DHTBZ, [+]-α-HTBZ) is a potent, highly selective VMAT2 inhibitor (Ki=2 nM) and tetrabenazine metabolite. |
| PC-47109 |
GZ-794A
VMAT2 inhibitor
|
GZ-794A is a potent, selective inhibitor of vesicular monoamine transporter-2 (VMAT2) with Ki of 30 nM, inhibits methamphetamine-evoked endogenous dopamine release with IC50 of 0.4 uM, shows potential for treatment for methamphetamine abuse. |
| PC-47108 |
GZ-793A
VMAT2 inhibitor
|
GZ-793A is a potent, selective inhibitor of vesicular monoamine transporter-2 (VMAT2) with Ki of 30 nM, inhibits methamphetamine-evoked endogenous dopamine release with IC50 of 10.6 uM. |
| PC-47107 |
GZ-11608
VMAT2 inhibitor
|
GZ-11608 is a potent and selective vesicular monoamine transporter-2 (VMAT2) inhibitor with Ki of 25 nM, GZ-11608 (EC50=620 nM) released vesicular dopamine 25-fold less potently than it inhibited VMAT2 dopamine uptake. |
| PC-43400 |
Vanoxerine
Dopamine transport inhibitor
|
Vanoxerine (GBR-12909, I-893, Boxeprazine) is a highly potent inhibitor of dopamine uptake in vitro in tissue slices obtained from rat neostriatum with IC50 of 40-50 nM, also inhibits norepinephrine uptake with IC50 of 560-2600 nM. |
| PC-43399 |
Vanoxerine dihydrochloride
Dopamine transport inhibitor
|
Vanoxerine (GBR-12909, I-893, Boxeprazine) is a highly potent inhibitor of dopamine uptake in vitro in tissue slices obtained from rat neostriatum with IC50 of 40-50 nM, also inhibits norepinephrine uptake with IC50 of 560-2600 nM. |
| PC-60053 |
Solriamfetol hydrochloride
|
Solriamfetol hydrochloride (JZP-110, R-228060, ADX-N05, YKP-10A) is a norepinephrine-dopamine reuptake inhibitor that inhibits dopamine and norepinephrine transporter with IC50 of 2.9 and 4.4 uM, respectively. |
| PC-46649 |
Paroxetine hydrochloride
|
Paroxetine hydrochloride (BRL29060 hydrochloride) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. |
| PC-45454 |
Amitifadine hydrochloride
|
Amitifadine hydrochloride (DOV-21947 hydrochloride) is a triple monoamine reuptake inhibitor that inhibits the reuptake of [3H]serotonin, [3H]norepinephrine, and [3H]dopamine in HEK 293 cells expressing the corresponding human recombinant transporters (IC50 values of 12, 23, and 96 nM, respectively). |
| PC-22519 |
Escitalopram
SERT inhibitor
|
Escitalopram ((S)-Citalopram) is a potent, selective serotonin reuptake inhibitor with Ki of 0.89 nM (SERT), shows selectivity over both dopamine transporter (DAT) and norepinephrine transporter (NET). |
| PC-22426 |
SRI-30827
DAT modualtor
|
SRI-30827 is a selective, allosteric modulator of dopamine transporter (DAT), inhibits DA uptake in rat synaptosomes with IC50 of 0.5 nM, counteracts Tat-induced potentiation of cocaine reward. |
