| Cat. No. |
Product Name |
Information |
| PC-47108 |
GZ-793A
VMAT2 inhibitor
|
GZ-793A is a potent, selective inhibitor of vesicular monoamine transporter-2 (VMAT2) with Ki of 30 nM, inhibits methamphetamine-evoked endogenous dopamine release with IC50 of 10.6 uM. |
| PC-47107 |
GZ-11608
VMAT2 inhibitor
|
GZ-11608 is a potent and selective vesicular monoamine transporter-2 (VMAT2) inhibitor with Ki of 25 nM, GZ-11608 (EC50=620 nM) released vesicular dopamine 25-fold less potently than it inhibited VMAT2 dopamine uptake. |
| PC-38458 |
Nisoxetine hydrochloride
SNRI
|
Nisoxetine Hcl is a highly selective and potent noradrenaline reuptake inhibitor (SNRI) with high affinity for the NET (0.7 nM), shows potential antidepressant effect. |
| PC-73425 |
lafadofensine
Monoamines reuptake inhibitor
|
Lafadofensine is a small molecule monoamines reuptake inhibitor with antidepressant activity. |
| PC-35618 |
SRI-31142
DAT inhibitor
|
SRI-31142 (SRI31142) is a novel potent, putative allosteric dopamine transporter (DAT) inhibitor with Ki of 1.9 nM.. |
| PC-35476 |
CTDP-32476
DAT inhibitor
|
CTDP-32476 is a potent and selective dopamine transporter (DAT) inhibitor and a competitive inhibitor of cocaine binding to the DAT with Ki of 12 nM. |
| PC-35438 |
Ampreloxetine
Monoamine reuptake inhibitor
|
Ampreloxetine (TD-9855) is a potent monoamine reuptake inhibitor with pIC50 of 8.0, 8.6 and 6.8 for human NET, SERT, and DAT, respectively. |
| PC-63567 |
AMR-2
Triple reuptake inhibitor
|
AMR-2 is a highly potent, orally active, triple reuptake inhibitor of SERT, NET, and DAT with IC50 of 3.0, 3.1, and 8.3 nM, respectively. |
| PC-43400 |
Vanoxerine
Dopamine transport inhibitor
|
Vanoxerine (GBR-12909, I-893, Boxeprazine) is a highly potent inhibitor of dopamine uptake in vitro in tissue slices obtained from rat neostriatum with IC50 of 40-50 nM, also inhibits norepinephrine uptake with IC50 of 560-2600 nM. |
| PC-43399 |
Vanoxerine dihydrochloride
Dopamine transport inhibitor
|
Vanoxerine (GBR-12909, I-893, Boxeprazine) is a highly potent inhibitor of dopamine uptake in vitro in tissue slices obtained from rat neostriatum with IC50 of 40-50 nM, also inhibits norepinephrine uptake with IC50 of 560-2600 nM. |
| PC-63053 |
Atomoxetine hydrochloride
NET inhibitor
|
Atomoxetine hydrochloride((R)-Tomoxetine LY-139603) is a potent, selective norepinephrine (NE) transporter inhibitor with Ki of 5 nM. |
| PC-63052 |
Atomoxetine
NET inhibitor
|
Atomoxetine ((R)-Tomoxetine, LY-139603) is a potent, selective norepinephrine (NE) transporter inhibitor with Ki of 5 nM. |
