| Cat. No. |
Product Name |
Information |
| PC-24214 |
Tetrabenazine
VMAT2 inhibitor
|
Tetrabenazine (Ro 1-9569) is a potent, reversible inhibitor of the vesicular monoamine transporter VMAT2 with Kd of 1.34 nM, shows potential for diseases related to hyperactive movement disorders such as Huntington's disease. |
| PC-24213 |
Deutetrabenazine
VMAT2 inhibitor
|
Deutetrabenazine is an inhibitor of vesicular monoamine transporter type 2 (VMAT2), depletes presynaptic dopamine and is useful in the treatment of hyperkinetic movement disorders. |
| PC-24119 |
Nomifensine
Monoamine reuptake inhibitor
|
Nomifensine is a norepinephrine-dopamine reuptake inhibitor, increases the amount of synaptic norepinephrine and dopamine available to receptors by blocking the dopamine and norepinephrine reuptake transporters. |
| PC-24118 |
Cendifensine
Monoamine reuptake inhibitor
|
Cendifensine is a triple monoamine reuptake inhibitor. |
| PC-23760 |
Paroxetine
GRK2 inhibitor, SSRI
|
Paroxetine hydrochloride is an oral, selective serotonin reuptake inhibitor (SSRI), also is a direct, selective inhibitor of G protein-coupled receptor kinase 2 (GRK2) with pIC50 of 5.6. |
| PC-23147 |
Citalopram
SSRI
|
Citalopram is an orally active selective serotonin reuptake inhibitor (SSRI), shows antidepressant and enhances serotoninergic neurotransmission. |
| PC-22974 |
MRS7232
DAT inhibitor
|
MRS7232 is an allosteric, non-competitive inhibitor of human dopamine transporter (DAT) with EC50 of 34 nM, and norepinephrine transporter (NET), also is a potent A3AR agonist with Ki of 14.5 nM. |
| PC-22973 |
MRS7292
DAT inhibitor
|
MRS7292 is an allosteric, non-competitive inhibitor of human dopamine transporter (DAT) with EC50 of 35 nM, and norepinephrine transporter (NET), also is a potent A3AR agonist with Ki of 5.38 nM. |
| PC-22519 |
Escitalopram
SERT inhibitor
|
Escitalopram ((S)-Citalopram) is a potent, selective serotonin reuptake inhibitor with Ki of 0.89 nM (SERT), shows selectivity over both dopamine transporter (DAT) and norepinephrine transporter (NET). |
| PC-22426 |
SRI-30827
DAT modualtor
|
SRI-30827 is a selective, allosteric modulator of dopamine transporter (DAT), inhibits DA uptake in rat synaptosomes with IC50 of 0.5 nM, counteracts Tat-induced potentiation of cocaine reward. |
| PC-22149 |
IP2015 hydrochloride
Monoamine reuptake inhibitor
|
IP2015 (IPED2015, Pudafensine, NS18313) hydrochloride is a novel monoamine transport inhibitor with IC50 of 9.5, 72.0 and 3.8 nM for hSET, hNAT and hDAT respectively, inhibits dopamine uptake and binds to DAT. |
| PC-22148 |
IP2015
Monoamine reuptake inhibitor
|
IP2015 (IPED2015, Pudafensine, NS18313) is a novel monoamine transport inhibitor with IC50 of 9.5, 72.0 and 3.8 nM for hSET, hNAT and hDAT respectively, inhibits dopamine uptake and binds to DAT. |
