| Cat. No. |
Product Name |
Information |
| PC-21191 |
LQFM215
SLC6A7 inhibitor
|
LQFM215 (LQFM-215) is a synthetic L-proline transporter (PROT/SLC6A7) inhibitor, inhibits proline uptake in hippocampal synaptosome with IC50 of 20.4 uM, present neuroprotective potential. |
| PC-49734 |
RRR-DHTBZ camphorsulfonic acid salt
VMAT2 inhibitor
|
RRR-dihydrotetrabenazine (RRR-DHTBZ, [+]-α-HTBZ) is a potent, highly selective VMAT2 inhibitor (Ki=2 nM) and tetrabenazine metabolite. |
| PC-47109 |
GZ-794A
VMAT2 inhibitor
|
GZ-794A is a potent, selective inhibitor of vesicular monoamine transporter-2 (VMAT2) with Ki of 30 nM, inhibits methamphetamine-evoked endogenous dopamine release with IC50 of 0.4 uM, shows potential for treatment for methamphetamine abuse. |
| PC-47108 |
GZ-793A
VMAT2 inhibitor
|
GZ-793A is a potent, selective inhibitor of vesicular monoamine transporter-2 (VMAT2) with Ki of 30 nM, inhibits methamphetamine-evoked endogenous dopamine release with IC50 of 10.6 uM. |
| PC-47107 |
GZ-11608
VMAT2 inhibitor
|
GZ-11608 is a potent and selective vesicular monoamine transporter-2 (VMAT2) inhibitor with Ki of 25 nM, GZ-11608 (EC50=620 nM) released vesicular dopamine 25-fold less potently than it inhibited VMAT2 dopamine uptake. |
| PC-60053 |
Solriamfetol hydrochloride
|
Solriamfetol hydrochloride (JZP-110, R-228060, ADX-N05, YKP-10A) is a norepinephrine-dopamine reuptake inhibitor that inhibits dopamine and norepinephrine transporter with IC50 of 2.9 and 4.4 uM, respectively. |
| PC-46649 |
Paroxetine hydrochloride
|
Paroxetine hydrochloride (BRL29060 hydrochloride) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. |
| PC-45454 |
Amitifadine hydrochloride
|
Amitifadine hydrochloride (DOV-21947 hydrochloride) is a triple monoamine reuptake inhibitor that inhibits the reuptake of [3H]serotonin, [3H]norepinephrine, and [3H]dopamine in HEK 293 cells expressing the corresponding human recombinant transporters (IC50 values of 12, 23, and 96 nM, respectively). |
| PC-22149 |
IP2015 hydrochloride
Monoamine reuptake inhibitor
|
IP2015 (IPED2015, Pudafensine, NS18313) hydrochloride is a novel monoamine transport inhibitor with IC50 of 9.5, 72.0 and 3.8 nM for hSET, hNAT and hDAT respectively, inhibits dopamine uptake and binds to DAT. |
| PC-22148 |
IP2015
Monoamine reuptake inhibitor
|
IP2015 (IPED2015, Pudafensine, NS18313) is a novel monoamine transport inhibitor with IC50 of 9.5, 72.0 and 3.8 nM for hSET, hNAT and hDAT respectively, inhibits dopamine uptake and binds to DAT. |
| PC-22086 |
JPC-141 hydrochloride
VMAT2 inhibitor
|
JPC-141 hydrochloride is a potent, selective vesicular monoamine transporter-2 (VMAT2) inhibitor, potently inhibits [3H]dopamine uptake by VMAT2 in striatal vesicles with Ki of 52 nM. |
| PC-22085 |
JPC-141
VMAT2 inhibitor
|
JPC-141 is a potent, selective vesicular monoamine transporter-2 (VMAT2) inhibitor, potently inhibits [3H]dopamine uptake by VMAT2 in striatal vesicles with Ki of 52 nM. |
