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Cat. No. Product Name Information
PC-26014

BRI-50460

cPLA2 inhibitor

BRI-50460 is a potent, selective and brain-penetrant cytosolic calcium-dependent phospholipase A2 (cPLA2) inhibitor with IC50 of 0.88 nM for cellular arachidonic acid (AA) release and 4.1 nM for downstream PGE2 production.
PC-25982

AACOCF3

cPLA2 inhibitor

Arachidonyl trifluoromethyl ketone (AACOCF3) is an arachidonic acid analog and potent and selective, slow- and tight-binding inhibitor of cytosolic phospholipase A2 (cPLA2), inhibits the release of AA from calcium ionophore-challenged U937 cells (IC50= 8 uM) and from platelets (IC50=2 uM).
PC-25738

ONO-RS-082

PLA2 inhibitor

ONO-RS-082 is a specific phospholipase A2 (PLA2) inhibitor with IC50 of 1.0 uM, does not inhibit PKC.
PC-24356

ABD778

ABHD17 inhibitor

ABD778 is a potent and selective, in vivo-active ABHD17 inhibitor with IC50 of 76 nM and 84 nM for both human and mouse ABHD17 enzymes, respectively, is the isopropyl ester analog of ABD957.

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