| Cat. No. |
Product Name |
Information |
| PC-49071 |
VU0364739
PLD2 inhibitor
|
VU0364739 is a potent, selective allosteric inhibitor of phospholipase D2 (PLD2) with cellular IC50 of 20 nM, >75-fold selectivity over PLD1. |
| PC-38837 |
Silibinin A
PLCβ3 inhibitor
|
Silibinin (Silibinin A) is a flavonolignan isolated from milk thistle, Silybum marianum, that has been shown to exhibit antioxidant and antineoplastic activities, targets phospholipase C beta 3 (PLCβ3). |
| PC-38749 |
ABD298
ABHD13 inhibitor
|
ABD298 is a potent, selective ABHD13 inhibitor, inhibits HEK293T cells expressing recombinant mouse ABHD13 with IC50 of 0.98 uM. |
| PC-38533 |
ML226
ABHD11 inhibitor
|
ML226 (ML-226) is a potent, selective, covalent inhibitor of α/β hydrolase domain-containing protein 11 (ABHD11) with IC50 values of 15 and 0.68 nM in vitro and in situ, respectively. |
| PC-38505 |
ML211
LYPLA1/LYPLA2 inhibitor
|
ML211 (ML-211) is a potent, selective, dual Lysophospholipase 1 / Lysophospholipase 2 (LYPLA1/LYPLA2, APT1/APT2) inhibitor with IC50 of 17/31 nM, respectively, displays no activity against ABHD11 and other 20 serine hydrolases. |
| PC-38483 |
YM26734
sPLA2 inhibitor
|
YM-26734 (YM26734) is a potent, selective and competitive inhibitor of extracellular group II phospholipase A2 (sPLA2) with IC50 of 85 nM (rabbit platelet-derived group II), >70-fold selectivity over group I PLA2. |
| PC-72955 |
VU0285655-1
PLD2 inhibitor
|
VU0285655-1 (BML280) is a potent, selective inhibitor of PLD2, prevents caspase-3 cleavage and reduction in cell viability induced by high glucose, induces autophagy in colorectal cancer cells. |
| PC-72954 |
VU0359595
PLD1 inhibitor
|
VU0359595 (VU 0359595) is a potent, selective phospholipase D (PLD) inhibitor with cell IC50 of 4 nM. |
| PC-38219 |
LEI-401
NAPE-PLD inhibitor
|
LEI-401 (LEI 401) is a potent, selective, brain active N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) inhibitor with Ki of 2.7 nM. |
| PC-36162 |
AK106-001616
cPLA2 inhibitor
|
AK106-001616 (AK 106-001616) is a potent and selective inhibitor of cytosolic phospholipase A2 (cPLA2) with IC50 of 3.8 nM (human cPLA2 enzyme). |
| PC-36138 |
FKGK18
GVIA iPLA2 inhibitor
|
FKGK18 (FKGK-18) is a potent, selective inhibitor of iPLA2 (group VIA Ca2+-independent phospholipase A2) with IC50 of 50 nM. |
| PC-36137 |
GK563
GVIA iPLA2 inhibitor
|
GK563 (GK-563) is a potent, selective inhibitor of Ca2+-independent phospholipase A2 (GVIA iPLA2) with IC50 of 1 nM, >20,000-fold selectivity over GIVA cPLA2. |
