| Cat. No. |
Product Name |
Information |
| PC-62137 |
ML298
PLD2 inhibitor
|
ML298 is a potent, selective phospholipase PLD2 inhibitor with IC50 of 355 nM, displays >53-fold selectivity over PLD1 (IC50>20 uM). |
| PC-62136 |
ML299
PLD1/PLD2 inhibitor
|
ML299 (VU0463568) is a potent, CNS penetrant, dual phospholipase PLD1/PLD2 probe inhibitor with IC50 of 6 nM/20 nM, respectively. |
| PC-61846 |
PF 5212372
cPLA2 inhibitor
|
PF 5212372 (PLA-950, ZPL-521, ZPL 5212372) is a potent, selective inhibitor of cPLA2 (cytosolic phospholipase A2α) with IC50 of 7 nM. |
| PC-61845 |
Efipladib
cPLA2α inhibitor
|
Efipladib (PLA 902) is a potent, selective and orally active inhibitor of cPLA2α with IC50 of 20 nM for LTB4 inhibition. |
| PC-61844 |
Ecopladib
cPLA2α inhibitor
|
Ecopladib (PLA 725) is a potent, selective and orally active inhibitor of cPLA2α with IC50 of 0.15 and 0.11 uM in GLU micelle and rat whole blood assays, respectively. |
| PC-61843 |
Pyrrophenone
cPLA2α inhibitor
|
Pyrrophenone is a potent cPLA2α inhibitor with enzyme IC50 of 4.2 nM. |
| PC-61842 |
WAY-196025
cPLA2α inhibitor
|
WAY-196025 is a potent, selective, and orally active inhibitor of cPLA2α with IC50 of 12 nM for LTB4 inhibition. |
| PC-61840 |
KT-195
ABHD6 inhibitor
|
KT-195 is a potent and selective inhibitor of serine hydrolase ABHD6 (α/β-hydrolase domain-containing protein 6) with IC50 of 10 nM. |
| PC-60917 |
ML349
APT2 inhibitor
|
ML349 is a potent, specific acyl protein thioesterase 2 (APT-2, LYPLA2) inhibitor with IC50 of 144 nM and Ki of 120 nM, >20-fold selectivity over APT-1 and serine hydrolase enzyme family. |
| PC-60713 |
ASB 14780
cPLA2α inhibitor
|
ASB 14780 (ASB14780, ASB-14780) is a potent, selective and orally active cytosolic phospholipase A2α (cPLA2α) inhibitor with IC50 of 20 nM. |
| PC-60457 |
AZD2716
sPLA2 inhibitor
|
AZD2716 (AZD-2716) is a novel potent, selective, orally bioavailable sPLA2 inhibitor with excellent plasma sPLA2 inhibition (IC50=0.1 nM). |
| PC-70212 |
Rilapladib
Lp-PLA2 inhibitor
|
Rilapladib (SB-659032, SB659032) is a potent, selective and oral lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with IC50 of 0.23 nM, for the treatment of Alzheimer's disease and atherosclerosis.. |
