| Cat. No. |
Product Name |
Information |
| PC-61844 |
Ecopladib
cPLA2α inhibitor
|
Ecopladib (PLA 725) is a potent, selective and orally active inhibitor of cPLA2α with IC50 of 0.15 and 0.11 uM in GLU micelle and rat whole blood assays, respectively. |
| PC-61843 |
Pyrrophenone
cPLA2α inhibitor
|
Pyrrophenone is a potent cPLA2α inhibitor with enzyme IC50 of 4.2 nM. |
| PC-61842 |
WAY-196025
cPLA2α inhibitor
|
WAY-196025 is a potent, selective, and orally active inhibitor of cPLA2α with IC50 of 12 nM for LTB4 inhibition. |
| PC-61840 |
KT-195
ABHD6 inhibitor
|
KT-195 is a potent and selective inhibitor of serine hydrolase ABHD6 (α/β-hydrolase domain-containing protein 6) with IC50 of 10 nM. |
| PC-60917 |
ML349
APT-2 inhibitor
|
ML349 is a potent, specific acyl protein thioesterase 2 (APT-2, LYPLA2) inhibitor with IC50 of 144 nM and Ki of 120 nM, >20-fold selectivity over APT-1 and serine hydrolase enzyme family. |
| PC-60713 |
ASB 14780
cPLA2α inhibitor
|
ASB 14780 (ASB14780, ASB-14780) is a potent, selective and orally active cytosolic phospholipase A2α (cPLA2α) inhibitor with IC50 of 20 nM. |
| PC-60457 |
AZD2716
sPLA2 inhibitor
|
AZD2716 (AZD-2716) is a novel potent, selective, orally bioavailable sPLA2 inhibitor with excellent plasma sPLA2 inhibition (IC50=0.1 nM). |
| PC-70212 |
Rilapladib
Lp-PLA2 inhibitor
|
Rilapladib (SB-659032, SB659032) is a potent, selective and oral lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with IC50 of 0.23 nM, for the treatment of Alzheimer's disease and atherosclerosis.. |
| PC-42240 |
ML348
APT-1 inhibitor
|
ML348 is a potent, selective Acyl protein thioesterase 1 (APT-1, LYPLA1) with IC50 of 210 nM, displays >10-fold selectivity over APT-2, >47-fold selectivity over a panel of >20 serine hydrolases. |
| PC-45957 |
SPK-601
PC-PLC inhibitor
|
SPK-601 (LMV-601) is a potent phosphatidylcholine-specific phospholipase C (PC-PLC) inhibitor. |
| PC-42634 |
Darapladib
Lp-PLA2 inhibitor
|
Darapladib (SB480848) is a potent Lp-PLA2 inhibitor with IC50 of 0.25 nM, shows an enhanced in vitro and in vivo profile versus SB-435495. |
| PC-42702 |
CAY10650
cPLA2α inhibitor
|
CAY10650 is a highly potent cytosolic phospholipase A2α (cPLA2α) inhibitor with an IC50 of 12 nM. |
