| Cat. No. |
Product Name |
Information |
| PC-63003 |
SB-435495
Lp-PLA2 inhibitor
|
SB-435495 (SB435495) is a potent, orally active inhibitor of Lp-PLA2 with IC50 of 0.06 nM. |
| PC-62407 |
LYPLAL1-IN-11
LYPLAL1 inhibitor
|
LYPLAL1-IN-11 is a potent, selective, covalent inhibitor of lysophospholipase-like 1 (LYPLAL1) with IC50 of 6 nM. |
| PC-62332 |
ML378
APT1/APT2 inhibitor
|
ML378 (CID71710938, JJH-254) is an in vivo active carbamate-based dual inhibitor of lysophospholipase LYPLA1 (APT1) and LYPLA2 (APT2) with IC50 of 122 nM and 245 nM, repectively. |
| PC-62262 |
KC01
ABHD16A inhibitor
|
KC01 is a potent and selective inhibitor of ABHD16A with IC50 of 90 nM for hABHD16A, 520 nM for mABHD16A. |
| PC-62138 |
ML395
PLD2 inhibitor
|
ML395 is a potent, selective, allosteric phospholipase D2 (PLD2) inhibitor with cellular IC50 of 360 nM, shows >80-fold selectivity over PLD1 (IC50>30 uM). |
| PC-62137 |
ML298
PLD2 inhibitor
|
ML298 is a potent, selective phospholipase PLD2 inhibitor with IC50 of 355 nM, displays >53-fold selectivity over PLD1 (IC50>20 uM). |
| PC-62136 |
ML299
PLD1/PLD2 inhibitor
|
ML299 (VU0463568) is a potent, CNS penetrant, dual phospholipase PLD1/PLD2 probe inhibitor with IC50 of 6 nM/20 nM, respectively. |
| PC-61846 |
PF-5212372
cPLA2 inhibitor
|
PF-5212372 (PLA-950, ZPL-521, ZPL 5212372) is a potent, selective inhibitor of cPLA2 (cytosolic phospholipase A2α) with IC50 of 7 nM. |
| PC-61845 |
Efipladib
cPLA2α inhibitor
|
Efipladib (PLA902) is a potent, selective and orally active inhibitor of cPLA2α with IC50 of 20 nM for LTB4 inhibition. |
| PC-61844 |
Ecopladib
cPLA2α inhibitor
|
Ecopladib (PLA 725) is a potent, selective and orally active inhibitor of cPLA2α with IC50 of 0.15 and 0.11 uM in GLU micelle and rat whole blood assays, respectively. |
| PC-61843 |
Pyrrophenone
cPLA2α inhibitor
|
Pyrrophenone is a potent cPLA2α inhibitor with enzyme IC50 of 4.2 nM. |
| PC-61842 |
WAY-196025
cPLA2α inhibitor
|
WAY-196025 is a potent, selective, and orally active inhibitor of cPLA2α with IC50 of 12 nM for LTB4 inhibition. |
