| Cat. No. |
Product Name |
Information |
| PC-25365 |
ABD646
ABHD18 inhibitor
|
ABD646 is a selective, covalent, small-molecule inhibitor of ABHD18, rescues TAFAZZIN (TAZ) mutant phenotypes in fibroblasts from human patients and in fish embryos. |
| PC-23791 |
AVX420
cPLA2α inhibitor
|
AVX420 (GK420) is a potent and selective inhibitor of Group IVA cytosolic phospholipase A2 (cPLA2α), inhibits arachidonic acid (AA) release in IL-1β-stimulated SW982 synoviocyte with IC50 of 0.09 uM. |
| PC-22786 |
Giripladib
cPLA2 inhibitor
|
Giripladib (PLA-695) is a potent, specific cytoplasmic phospholipase A2 (cPLA2). |
| PC-22189 |
AX048
cPLA2 inhibitor
|
AX048 is a potent cytosolic group IVA phospholipase A2 (cPLA2) with analgesic effect. |
| PC-20921 |
VU534
NAPE-PLD activator
|
VU534 is a small molecule activator of N-acyl-phosphatidylethanolamine hydrolyzing phospholipase D (NAPE-PLD) with EC50 of 0.3 uM, enhances efferocytosis by macrophages. |
| PC-20134 |
ABHD6 inhibitor 22f
ABHD6 inhibitor
|
ABHD6 inhibitor 22f is a potent, selective ABHD6 inhibitor with IC50 of 8.0 nM (hABHD6), does not inhibit hMGL and hFAAH. |
| PC-20133 |
KT203
ABHD6 inhibitor
|
KT203 (KT-203) is a potent, selective inhibitor of α/β-hydrolase domain 6 (ABHD6) with IC50 of 3.9 nM in 2-AG hydrolysis assays. |
| PC-20132 |
WWL70
ABHD6 inhibitor
|
WWL70 is a potent selective inhibitor of α/β-hydrolase domain 6 (ABHD6) with IC50 of 70 nM. |
| PC-20131 |
KT185
ABHD6 inhibitor
|
KT185 (KT-185) is a potent, selective, irreversible and orally-active α/β-hydrolase domain 6 (ABHD6) inhibitor with IC50 of 0.21 nM. |
| PC-20130 |
KT182
ABHD6 inhibitor
|
KT-182 (KT182) is a potent, selective, irreversible α/β-hydrolase domain 6 (ABHD6) inhibitor with IC50 of 1.7 nM. |
| PC-20129 |
JZP-430
ABHD6 inhibitor
|
JZP-430 (JZP430) is potent, selective and irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) with IC50 of 44 nM (hABHD6), 230-fold selectivity over FAAH and lysosomal acid lipase (LAL). |
| PC-20128 |
UCM710
FAAH/ABHD6 inhibitor
|
UCM710 (Glycidyl Palmitoleate, UCM 710) is a potent, dual inhibitor of FAAH and ABHD6, inhibits both AEA and 2-AG hydrolysis in neuron homogenates with IC50 of 1.2 and 0.4 uM respectively, without significantly affecting MAGL activity. |
