| Cat. No. |
Product Name |
Information |
| PC-42240 |
ML348
APT-1 inhibitor
|
ML348 is a potent, selective Acyl protein thioesterase 1 (APT-1, LYPLA1) with IC50 of 210 nM, displays >10-fold selectivity over APT-2, >47-fold selectivity over a panel of >20 serine hydrolases. |
| PC-45957 |
SPK-601
PC-PLC inhibitor
|
SPK-601 (LMV-601) is a potent phosphatidylcholine-specific phospholipase C (PC-PLC) inhibitor. |
| PC-42634 |
Darapladib
Lp-PLA2 inhibitor
|
Darapladib (SB480848) is a potent Lp-PLA2 inhibitor with IC50 of 0.25 nM, shows an enhanced in vitro and in vivo profile versus SB-435495. |
| PC-42702 |
CAY10650
cPLA2α inhibitor
|
CAY10650 is a highly potent cytosolic phospholipase A2α (cPLA2α) inhibitor with an IC50 of 12 nM. |
| PC-45953 |
D609
PC-PLC inhibitor, SMS inhibitor
|
D609 is a competitive inhibitor of PC-PLC with Ki of 6.4 uM, also is a small molecule of sphingomyelin synthase (SMS1 and SMS2). |
| PC-23014 |
SLC13A3 inhibitor ACA
SLC13A3 inhibitor, PLA2 inhibitor
|
SLC13A3 inhibitor ACA ((E/Z)-BML264) is a small molecule inhibitor of SLC13A3, also is a broad spectrum Phospholipase A2 (PLA2) inhibitor and TRP channel blocker. |
| PC-22786 |
Giripladib
cPLA2 inhibitor
|
Giripladib (PLA-695) is a potent, specific cytoplasmic phospholipase A2 (cPLA2).
PLA-695 inhibits radiation induced phosphorylation of ERK and Akt in cultured endothelial cells. |
| PC-20922 |
VU533
NAPE-PLD activator
|
VU533 is a small molecule activator of N-acyl-phosphatidylethanolamine hydrolyzing phospholipase D (NAPE-PLD) with EC50 of 0.3 uM, enhances efferocytosis by macrophages. |
| PC-20921 |
VU534
NAPE-PLD activator
|
VU534 is a small molecule activator of N-acyl-phosphatidylethanolamine hydrolyzing phospholipase D (NAPE-PLD) with EC50 of 0.3 uM, enhances efferocytosis by macrophages. |
