| Cat. No. |
Product Name |
Information |
| PC-61840 |
KT195
ABHD6 inhibitor
|
KT195 (ML 295) is a potent and selective inhibitor of serine hydrolase ABHD6 (α/β-hydrolase domain-containing protein 6) with IC50 of 10 nM. |
| PC-60917 |
ML349
APT2 inhibitor
|
ML349 is a potent, specific acyl protein thioesterase 2 (APT-2, LYPLA2) inhibitor with IC50 of 144 nM and Ki of 120 nM, >20-fold selectivity over APT-1 and serine hydrolase enzyme family. |
| PC-60713 |
ASB14780
cPLA2α inhibitor
|
ASB14780 (ASB-14780) is a potent, selective and orally active cytosolic phospholipase A2α (cPLA2α) inhibitor with IC50 of 20 nM. |
| PC-60457 |
AZD2716
sPLA2 inhibitor
|
AZD2716 (AZD-2716) is a novel potent, selective, orally bioavailable sPLA2 inhibitor with excellent plasma sPLA2 inhibition (IC50=0.1 nM). |
| PC-70212 |
Rilapladib
Lp-PLA2 inhibitor
|
Rilapladib (SB-659032, SB659032) is a potent, selective and oral lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with IC50 of 0.23 nM, for the treatment of Alzheimer's disease and atherosclerosis.. |
| PC-42240 |
ML348
APT-1 inhibitor
|
ML348 is a potent, selective Acyl protein thioesterase 1 (APT-1, LYPLA1) with IC50 of 210 nM, displays >10-fold selectivity over APT-2, >47-fold selectivity over a panel of >20 serine hydrolases. |
| PC-45957 |
SPK-601
PC-PLC inhibitor
|
SPK-601 (LMV-601) is a potent phosphatidylcholine-specific phospholipase C (PC-PLC) inhibitor. |
| PC-42634 |
Darapladib
Lp-PLA2 inhibitor
|
Darapladib (SB-480848) is a potent Lp-PLA2 inhibitor with IC50 of 0.25 nM, shows an enhanced in vitro and in vivo profile versus SB-435495. |
| PC-42702 |
CAY10650
cPLA2α inhibitor
|
CAY10650 is a highly potent cytosolic phospholipase A2α (cPLA2α) inhibitor with an IC50 of 12 nM. |
| PC-45953 |
D609
PC-PLC inhibitor, SMS inhibitor
|
D609 is a competitive inhibitor of PC-PLC with Ki of 6.4 uM, also is a small molecule of sphingomyelin synthase (SMS1 and SMS2). |
| PC-24356 |
ABD778
ABHD17 inhibitor
|
ABD778 is a potent and selective, in vivo-active ABHD17 inhibitor with IC50 of 76 nM and 84 nM for both human and mouse ABHD17 enzymes, respectively, is the isopropyl ester analog of ABD957. |
| PC-23014 |
SLC13A3 inhibitor ACA
SLC13A3 inhibitor, PLA2 inhibitor
|
SLC13A3 inhibitor ACA ((E/Z)-BML264) is a small molecule inhibitor of SLC13A3, also is a broad spectrum Phospholipase A2 (PLA2) inhibitor and TRP channel blocker. |
