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Cat. No. Product Name Information
PC-20328

BB-Cl-Amidine

pan-PAD inhibitor

BB-Cl-Amidine a peptidylarginine deminase (PAD) inhibitor, irreversibly inactivates all four PAD subtypes (kinact/KI=16,100, 4,100, 6,800, and 13,300 M-1min-1 for PAD1-4, respectively).
PC-49339

JBI-589

PAD4 inhibitor

JBI-589 (JBI589) is potent, selective, orally active PAD4 small molecule inhibitor, reduces CXCR2 expression and blocks neutrophil chemotaxis.
PC-38089

BMS-P5

PAD4 inhibitor

BMS-P5 is a potent, specific inhibitor of peptidylarginine deiminase 4 (PAD4) with IC50 of 98 nM.
PC-62217

GSK-199 hydrochloride

PAD4 inhibitor

GSK-199 hydrochloride is a potent, highly selective and reversible protein arginine deiminase PAD4 inhibitor with IC50 of 250 nM in FP binding assay (0.2 mM Ca), 200 nM in PAD4 NH3 release inhibition assay.
PC-62216

GSK-199

PAD4 inhibitor

GSK-199 is a potent, highly selective and reversible protein arginine deiminase PAD4 inhibitor with IC50 of 250 nM in FP binding assay (0.2 mM Ca), 200 nM in PAD4 NH3 release inhibition assay.
PC-62215

GSK-484 hydrochloride

PAD4 inhibitor

GSK-484 hydrochloride is a potent, highly selective and reversible protein arginine deiminase PAD4 inhibitor with IC50 of 80 nM in FP binding assay (0.2 mM Ca), 50 nM in PAD4 NH3 release inhibition assay.
PC-62214

GSK-484

PAD4 inhibitor

GSK-484 is a potent, highly selective and reversible protein arginine deiminase PAD4 inhibitor with IC50 of 80 nM in FP binding assay (0.2 mM Ca), 50 nM in PAD4 NH3 release inhibition assay.
PC-61919

Streptonigrin

Streptonigrin (Bruneomycin, NSC 45383) is a potent, selective, and irreversible PAD4 inactivator with IC50 of 1.87 uM, also binds directly to RAD54 with Kd of 9.1 uM, inhibits ATPase and DNA branch migration activity of RAD54.
PC-20331

ML325

pan-PAD inhibitor

ML325 (ML 325) is a potent, irreversible pan-protein arginine deiminase (PAD) inhibitor with IC50 of 70 nM, 200 nM 170 nM, and 240 nM for PAD1, 2, 3, and 4 in vitro respectively.
PC-20330

PAD4 inhibitor 24

PAD4 inhibitor 24 is a highly potent PAD4 inhibitor kinact/KI value of 54,000±3,000, displays >10-fold selectivity for PAD4 over PAD3 and >50-fold over PAD1 and PAD2.
PC-20329

PAD1 inhibitor 1

PAD1 inhibitor

PAD1 inhibitor 1 is a potent selective Protein Arginine Deiminase 1 (PAD1) inhibitor with IC50 of 18 uM for RFA labelling of PAD1 inhibition, kinact/KI value of 10,400 ± 2,380 M-1min-1.
PC-20327

PAD2 inhibitor 30a

PAD2 inhibitor 30a is a potent, selective protein arginine deiminase 2 (PAD2) inhibitor with IC50 of EC50 of 9.5 uM in target engagement assays in HEK293/PAD2 cells.

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