Cat. No. |
Product Name |
Information |
PC-20605 |
STAT3 inhibitor DG-4
TrxR1 inhibitor
|
DG-4 is a potent, selective inhibitor of STAT3-dependent transcription with IC50 of 0.12 uM in IL6-STAT3 luciferase reporter assays, 44-fold selectivity over IFN-γ STAT1. |
PC-38627 |
STAT3 inhibitor N4
STAT3 inhibitor
|
STAT3 inhibitor N4 is a small molecule capable of inhibiting the STAT3 SH2 domain with IC50 of 0.57 uM, SPR KD of 1.04 uM, inhibits STAT3 dimerization and transcription in vitro and suppresses pancreatic cancer in vivo. |
PC-70276 |
OPB-51602
|
A novel small molecule SH2 domain-targeting STAT3 inhibitor with IC50/Kd of 7.3/5 nM. |