| Cat. No. |
Product Name |
Information |
| PC-45439 |
KX1-004
Src inhibitor
|
KX1-004 is a non-ATP competitive Src-PTK inhibitor with IC50 of 40 uM. |
| PC-42539 |
KX2-391 mesylate
Src/pretubulin inhibitor
|
Tirbanibulin mesylate (KX2-391 mesylate) is a highly selective, non-ATP competitive substrate-pocket-directed Src/pretubulin inhibitor. |
| PC-42537 |
KX2-391
Src/tubulin inhibitor
|
KX2-391(Tirbanibulin, KX 01, KX 2-391) is a highly selective, non-ATP competitive substrate-pocket-directed Src/pretubulin inhibitor. |
| PC-24574 |
Src inhibitor PP1
Src inhibitor
|
PP1 is a potent, selective Src family tyrosine kinases inhibitor with IC50 of 5 and 6 nM for Lck and Fyn, respectively. |
| PC-24573 |
Src inhibitor PP2
Src inhibitor
|
PP2 is a potent, reversible and ATP-competitive Src family kinases inhibitor with IC50 of 4 and 5 nM for Lck and Fyn, respectively, also inhibits RIPK3 with IC50 of 29 nM. |
| PC-24043 |
Bosutinib hydrate
Src/Abl inhibitor
|
Bosutinib hydrate (SKI-606) is a potent, dual Src/Abl inhibitor with IC50 of 1.2 nM (Src enzyme), inhibits Src autophosphorylation with an IC50 of 0.25 uM in HT29 cells, inhibits bacterially expressed Abl kinase activity with IC50 of 1 nM. |
| PC-24042 |
Bosutinib
Src/Abl inhibitor
|
Bosutinib (SKI-606) is a potent, dual Src/Abl inhibitor with IC50 of 1.2 nM (Src enzyme), inhibits Src autophosphorylation with an IC50 of 0.25 uM in HT29 cells, inhibits bacterially expressed Abl kinase activity with IC50 of 1 nM. |
| PC-22492 |
(R)-LW-Srci-8
c-Src inhibitor
|
(R)-LW-Srci-8 is a potent, selective, covalent inhibitor of autophosphorylation site in c-Src kinase with IC50 of 35.83 nM. |
| PC-20792 |
A-420983
Lck inhibitor
|
A-420983 is a potent, orally active inhibitor of Lck kinase with IC50 of 37 nM, inhibits whole blood IL-2 production with IC50 of 7 nM. |
| PC-42434 |
TG 100801 hydrochloride
|
The prodrug of TG 100572, a potent, dual receptor tyrosine kinase/Src kinase inhibitor with IC50 of 2-16 nM for VEGFR, FGFR and PDGFR, 0.1-5 nM for Src family. |
| PC-42303 |
Src Inhibitor 1
|
A potent, selective dual site inhibitor of Src tyrosine kinase with Ki of 15 nM. |
| PC-42057 |
WEHI-345 analog
|
A potent Src inhibitor extracted from patent WO/2012003544A1.. |
