| Cat. No. |
Product Name |
Information |
| PC-61759 |
Foxy-5
Wnt5A agonist
|
Foxy-5 (formyl-Met-Asp-Gly-Cys-Glu-Leu) is a Wnt5A mimicking hexapeptide that inhibits breast cancer metastasis in vivo by targeting cell motility. |
| PC-70264 |
QS-11
ARFGAP1 inhibitor
|
QS-11 (QS11) is a small molecule inhibitor of GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) with Kd of 620 nM, synergizes the Wnt/beta-catenin signaling. |
| PC-70223 |
Prodigiosin
Wnt/β-catenin inhibitor
|
Prodigiosin is a natural red pigment produced by numerous bacterial species, has exhibited promising anticancer activity. |
| PC-45698 |
JW74
Wnt inhibitor
|
JW74 is an efficient and specific inhibitor of the canonical Wnt signaling with IC50 of 0.79 uM in ST-Luc assay. |
| PC-45774 |
BML-284
Wnt/β-catenin inhibitor
|
BML-284 (AMBMP) is a potent selective, and cell-permeable canonical Wnt/β-catenin pathway activator with EC50 of 0.7 uM (induces beta-catenin- and TCF-dependent transcriptional activity). |
| PC-42926 |
IWR-1
Wnt inhibitor
|
IWR-1 is a potent inhibitor of Wnt signaling with EC50 of 0.2 uM. |
| PC-22869 |
ETC-451
Wntless inhibitor
|
ETC-451 (ETC-2188451) is a specific small molecule inhibitor of the Wnt transporter Wntless (WLS/Evi) with IC50 of 7.7 uM in Wnt/β-catenin reporter assays in STF3A cells, blocks the interaction of Wnt with Wntless. |
| PC-22044 |
FQI2-34
LSF-β-catenin inhibitor
|
FQI2-34 is a small molecule inhibitor of late SV40 factor (LSF, encoded by TFCP2) and β-catenin interaction, suppresses Wnt activity in CRC cells. |
| PC-21946 |
CGK012
Wnt/β-catenin inhibitor
|
CGK012 is a small-molecule inhibitor of the Wnt/β-catenin signaling pathway, exerts antiseptic effects against HMGB1 septic responses. |
| PC-21892 |
ISQ-1
Wnt inhibitor
|
ISQ-1 is a potent in vitro inhibitor of several cancer cell lines (LS174T cell proliferation, IC50=100 nM), inhibits Wnt signaling and also activates adenosine monophosphate kinase (AMPK). |
| PC-21819 |
LPD-01
Importin7 inhibitor
|
LPD-01 is a small molecule inhibitor of the Wnt/β-catenin signaling pathway, directly binds to importin7, inhibits the transactivation of target genes of the Wnt/β-catenin signaling pathway. |
| PC-21485 |
KY02111
Wnt inhibitor
|
KY02111 is a small molecule canonical WNT signaling inhibitor, promotes differentiation of hPSCs to cardiomyocytes. |
