| Cat. No. |
Product Name |
Information |
| PC-45774 |
BML-284
Wnt/β-catenin inhibitor
|
BML-284 (AMBMP) is a potent selective, and cell-permeable canonical Wnt/β-catenin pathway activator with EC50 of 0.7 uM (induces beta-catenin- and TCF-dependent transcriptional activity). |
| PC-42926 |
IWR-1
Wnt inhibitor
|
IWR-1 is a potent inhibitor of Wnt signaling with EC50 of 0.2 uM. |
| PC-22044 |
FQI2-34
LSF-β-catenin inhibitor
|
FQI2-34 is a small molecule inhibitor of late SV40 factor (LSF, encoded by TFCP2) and β-catenin interaction, suppresses Wnt activity in CRC cells. |
| PC-21946 |
CGK012
Wnt/β-catenin inhibitor
|
CGK012 is a small-molecule inhibitor of the Wnt/β-catenin signaling pathway, exerts antiseptic effects against HMGB1 septic responses. |
| PC-21892 |
ISQ-1
Wnt inhibitor
|
ISQ-1 is a potent in vitro inhibitor of several cancer cell lines (LS174T cell proliferation, IC50=100 nM), inhibits Wnt signaling and also activates adenosine monophosphate kinase (AMPK). |
| PC-21819 |
LPD-01
Importin7 inhibitor
|
LPD-01 is a small molecule inhibitor of the Wnt/β-catenin signaling pathway, directly binds to importin7, inhibits the transactivation of target genes of the Wnt/β-catenin signaling pathway. |
| PC-21485 |
KY02111
Wnt inhibitor
|
KY02111 is a small molecule canonical WNT signaling inhibitor, promotes differentiation of hPSCs to cardiomyocytes. |
| PC-20651 |
Wnt-LRP5/6 inhibitor IC15
Wnt inhibitor
|
Wnt-LRP5/6 inhibitor IC15 is a potent Wnt inhibitor, binds to the Wnt binding site of LRP5/6 and inhibits Wnt signaling, causes significant decreases in proliferation and colony-forming efficiency. |
| PC-49509 |
YW2065
Wnt inhibitor
|
YW2065 is is a small molecule inhibitor of Wnt signaling by stabilizing Axin-1, also activates the tumor suppressor AMPK, demonstratesexcellent anti-CRC effects in vitro and in vivo. |
| PC-49508 |
SEN461
Wnt inhibitor
|
SEN461 (SEN 461) is a potent small molecule inhibitor of canonical WNT signaling, inhibits WNT reporter activity in the DBTRG cell line with IC50 of 1.3 uM, acts through AXIN stabilization. |
| PC-38719 |
C644-0303
Wnt/β-catenin inhibitor
|
C644-0303 is a novel Wnt/β-catenin signaling inhibitor (IC50=4.2 uM) with antitumor efficacy, inhibits both constitutive and ligand activated Wnt signals and its downstream gene expression. |
| PC-38354 |
Dalosirvat
Wnt modulator
|
Dalosirvat (SM04554) is a small-molecule Wnt pathway modulator, activates Wnt with IC50 of 28-29 nM, with potential topical treatment for androgenetic alopecia. |
