| Cat. No. |
Product Name |
Information |
| PC-43522 |
Dorsomorphin
AMPK inhibitor
|
Dorsomorphin (BML-275, Compound C) is a potent, selective and reversible AMPK inhibitor with Ki of 109 nM, shows no no significant activity on ZAPK, SYK, PKCθ, PKA and JAK3. |
| PC-43521 |
Dorsomorphin dihydrochloride
AMPK inhibitor
|
Dorsomorphin (BML-275, Compound C) is a potent, selective and reversible AMPK inhibitor with Ki of 109 nM, shows no no significant activity on ZAPK, SYK, PKCθ, PKA and JAK3. |
| PC-43520 |
AICAR phosphate
AMPK activator
|
AICAR phosphate (Acadesine, AICA Riboside, NSC 105823) is a selective AMPK activator in both hepatocytes and adipocytes. |
| PC-43519 |
AICAR
AMPK activator
|
AICAR (Acadesine, AICA Riboside, NSC 105823) is a selective AMPK activator in both hepatocytes and adipocytes. |
| PC-43240 |
Ampkinone
AMPK activator
|
Ampkinone is a small molecule activator of AMPK, stimulates the phosphorylation of AMPK via indirect activation of AMPK in various cell lines (2.7-fold at 10 uM). |
| PC-42982 |
HTH-01-015
NUAK1 inhibitor
|
HTH-01-015 is a potent, specific NUAK1 (AMPK-related kinase 5, ARK5) inhibitor with IC50 of 100 nM, displays >100-fold higher potency than NUAK2. |
| PC-62774 |
PF-06685249
AMPK activator
|
PF-06685249 (PF06685249, PF-249) is a novel potent, orally active, α1β1γ1/α2β1γ1-isoform selective AMPK activator with Kd of 14 nM, EC50 of 12 nM for α1β1γ1-AMPK. |
| PC-62773 |
PF-06679142
AMPK activator
|
PF-06679142 is a novel potent, orally active, α1β1γ1/α2β1γ1-isoform selective AMPK activator with Kd of 14 nM, EC50 of 22 nM for α1β1γ1-AMPK. |
| PC-62013 |
MK-3903
AMPK activator
|
MK-3903 is a potent and selective, direct and oral AMPK activator with EC50 of 9 nM. |
| PC-61181 |
MT47-100
AMPK inhibitor
|
MT47-100 is a novel potent, allosteric, simultaneously direct activator and inhibitor of AMPK complexes containing the β1 or β2 isoform, respectively. |
| PC-60632 |
PF-06409577
AMPK activator
|
PF-06409577(PF06409577, PF 6409577) is a potent, selective AMPK β1-containing isoforms activator with TR-FRET EC50 of 7.0 and 6.8 nM for α1β1γ1 and α2β1γ1, respectively. |
| PC-60202 |
AMPK activator 13
AMPK activator
|
AMPK activator 13 is a potent, allosteric, α1-selective small molecule activator of AMPK (EC50=20 nM). |
