| Cat. No. |
Product Name |
Information |
| PC-73284 |
HTH-02-006
NUAK2 inhibitor
|
HTH-02-006 is a potent, selective reversible inhibitor of NUAK1/2 with binding IC50 of 8/126 nM, respectively. |
| PC-36018 |
COH-SR4
AMPK activator
|
COH-SR4 (Mitochondria uncoupler SR4) is a bonafide uncoupler that induces energetic stress on cells, consequently leading to AMPK activation and mTOR inhibition without any effects on ERK/MEK MAPK signaling. |
| PC-35642 |
BL-AD008
AMPK activator
|
BL-AD008 (BL-AD 008) is a novel small molecule, dual-target activator targeting AMPK/ZIPK. |
| PC-35496 |
AMPK activator 991
AMPK activator
|
AMPK activator 991 is an allosteric AMPK activator, activates non-phosphorylated Thr172 AMPK in vitro, binds to α1β1γ1 and α2β1γ1 with Kd of 0.13 and 0.17 uM, respectively. |
| PC-35495 |
AMPK activator SC4
AMPK activator
|
AMPK activator SC4 is a potent, specific activator of α2β2-AMPK complexes with EC50 of 17.2 and 82.1 nM for α2β2γ1 and α2β2γ3, the predominant AMPK isoform complexes in human skeletal muscle. |
| PC-35414 |
GSK621
AMPK activator
|
GSK621 (GSK-621) is a potent, specific AMPK agonist (activator), induces cytotoxicity in AML (IC50=13-30 uM) but not in normal hematopoietic cells. |
| PC-35331 |
BAY-3827
AMPK inhibitor
|
BAY-3827 (BAY3827) is a potent, selective inhibitor of AMPK with IC50 of 0.4 nM (10 µM ATP) and 15 nM (2 mM ATP), respectively. |
| PC-43522 |
Dorsomorphin
AMPK inhibitor
|
Dorsomorphin (BML-275, Compound C) is a potent, selective and reversible AMPK inhibitor with Ki of 109 nM, shows no no significant activity on ZAPK, SYK, PKCθ, PKA and JAK3. |
| PC-43521 |
Dorsomorphin dihydrochloride
AMPK inhibitor
|
Dorsomorphin (BML-275, Compound C) is a potent, selective and reversible AMPK inhibitor with Ki of 109 nM, shows no no significant activity on ZAPK, SYK, PKCθ, PKA and JAK3. |
| PC-43520 |
AICAR phosphate
AMPK activator
|
AICAR phosphate (Acadesine, AICA Riboside, NSC 105823) is a selective AMPK activator in both hepatocytes and adipocytes. |
| PC-43519 |
AICAR
AMPK activator
|
AICAR (Acadesine, AICA Riboside, NSC 105823) is a selective AMPK activator in both hepatocytes and adipocytes. |
| PC-43240 |
Ampkinone
AMPK activator
|
Ampkinone is a small molecule activator of AMPK, stimulates the phosphorylation of AMPK via indirect activation of AMPK in various cell lines (2.7-fold at 10 uM). |
