| Cat. No. |
Product Name |
Information |
| PC-60599 |
ROC-325
Autophagy inhibitor
|
ROC-325 (ROC 325, ROC325) is a novel, orally available inhibitor of lysosomal-mediated autophagy. |
| PC-60217 |
AUTEN-67
MTMR14 inhibitor, autophagy inducer
|
AUTEN-67 is a small molecule autophagy enhancer that specificly inhibits myotubularin-related phosphatase MTMR14. |
| PC-70067 |
AUTEN-99
MTMR14 inhibitor, autophagy inducer
|
AUTEN-99 is a small molecule autophagy enhancer that inhibit the myotubularin-related phosphatase MTMR14/Jumpy. |
| PC-70066 |
AUTEN-99 hydrobromide
MTMR14 inhibitor, autophagy inducer
|
A small molecule autophagy enhancer that inhibit the myotubularin-related phosphatase MTMR14/Jumpy. |
| PC-45633 |
Hemin
Autophagy inducer
|
Hemin, a physiological erythroid maturation stimulator, is able to induce the expression of critical autophagic genes (Map1a1b (LC3), Beclin-1 gen, Atg5) in an erythroleukemia cell type. |
| PC-42080 |
SMER28
VCP/p97 activator
|
SMER28 is a small-molecule enhancer/inducer of Autophagy, SMER28 is a small molecule activator of VCP/p97. |
| PC-42248 |
STF-62247
Autophagy inducer
|
STF-62247 is a small molecule Autophagy inducer that induces autophagy and selectively induces lethality in VHL-deficient RCC cells. |
| PC-45515 |
SMER-18
Autophagy inducer
|
SMER-18 is a small molecule autophagy enhancer that induces autophagy independently of rapamycin in mammalian cells and enhances the clearance of autophagy substrates such as mutant huntingtin and A53T alpha-synuclein. |
| PC-23449 |
YT-6-2
p62/SQSTM1 agonist
|
YT-6-2 (YT 6-2) is a small molecule p62/SQSTM1 agonist and ligand, binds to the ZZ domain of the autophagic cargo receptor SQSTM1/p62, exerts antimicrobial efficacy. |
| PC-22903 |
Idroxioleic acid
Sphingomyelin synthase inducer
|
Idroxioleic acid (2-OHOA) is a first-in-class brain-penetrating synthetic hydroxylated lipid, activates sphingomyelin synthase (SMS) expression and regulates membrane-lipid composition and mitochondrial energy production, inducing cancer cell autophagy. |
| PC-22679 |
LC3in-C42
LC3A/B inhibitor
|
LC3in-C42 is a potent, covalent and cell-active LC3A/B inhibitor with IC50 of 7.6 nM in AlphaScreen assay, binds to LC3B selectively based on K49, potently inhibits autophagy. |
| PC-21907 |
Hycanthone
APE1 inhibitor
|
Hycanthone is a thioxanthenone DNA intercalator, inhibits RNA synthesis as well as the DNA topoisomerases I and II, inhibits apurinic endonuclease 1 (APE1) incision of depurinated plasmid DNA with IC50 of 80 nM. |
