Cat. No. |
Product Name |
Information |
PC-21443 |
CC-8977
CaMKK2 inhibitor
|
CC-8977 is a hgihly potent, selective inhibitor of calcium/calmodulin-dependent kinase kinase II (CaMKK2) with binding IC50 of 7 nM. |
PC-72972 |
AS105
CaMKII inhibitor
|
AS105 (AS-105) is a highly potent, ATP-competitive CaMKII inhibitor, inhibits CaMKIIδ with IC50 of 8 nM, Ki of 3 nM. |
PC-72971 |
GS-680
CaMKII inhibitor
|
GS-680 (GS680) is a novel selective and ATP-competitive CaMKII inhibitor with biochemical IC50 of 2.3 and 15.9 nM against CaMKIIδ and CaMKIIα, respectively. |
PC-72970 |
RA608
CaMKII inhibitor
|
RA608 (RA-608) is a potent, selective, ATP-competitive, orally available CaMKII inhibitor, inhibits human CaMKIIδ, CaMKIIɣ, CaMKIIα, and CaMKIIβ with IC50 of 22, 51, 121, and 1135 nM, respectively. |
PC-72969 |
RA306
CaMKII inhibitor
|
RA306 (RA-306) is a selective, potent, orally active, ATP-competitive CaMKII inhibitor, inhibits CaMKII delta (IC50=15 nM), gamma (IC50=25 nM), and alpha (IC50=61 nM) isoforms. |
PC-72949 |
TIM-063
CaMKK inhibitor
|
TIM-063 (TIM063) is a potent, selective, ATP-competitive CaMKK inhibitor with Ki of 0.35/0.2 uM for CaMKKα and CaMKKβ, respectively. |
PC-72909 |
CS640
CaMK1D inhibitor
|
CS640 (CS-640) is a potent, selective CaMK1D inhibitor with nanomolar range at both the enzymatic and cellular levels. |
PC-72908 |
CaMK1D-IN-18
CaMK1D inhibitor
|
CaMK1D-IN-18 is a potent, selective CaMK1D inhibitor with IC50 of 31 nM, >150-fold greater activity against CaMK1D than all non-CaMK1 kinases. |
PC-43468 |
KN-62
CaMK II inhibitor
|
KN-62 is a specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMK II) with Ki of 900 nM for rat brain CaMK II. |
PC-63352 |
CAMKK2 inhibitor 4t
CAMKK2 inhibitor
|
CAMKK2 inhibitor 4t is a potent, selective, orally available, brain-penetrant CAMKK2 inhibitor with pIC50 of 8.5. |
PC-45723 |
STO-609
CaMKK inhibitor
|
STO-609 is a selective and cell-permeable inhibitor of CaM-KK, inhibits recombinant CaM-KKα and CaM-KKβ with Ki of 80 and 15 ng/ml. |
PC-21505 |
SMP-114
CaMKII inhibitor
|
SMP-114 (Rimacalib) is a potent, specific and orally available CaMKII inhibitor with potential for treatment of rheumatoid arthritis. |