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Cat. No. Product Name Information
PC-42385

NS-638

Sodium channel inhibitor

NS-638 is a nonpeptide calcium channel blocker that dose dependently inhibits AMPA-stimulated [3H]GABA-release from cultured cortical neurons with IC50 of 4.3 uM.
PC-23959

SERCA1 inhibitor CKP2

SERCA1 inhibitor

SERCA1 inhibitor CKP2 is a novel specific inhibitor of sarco/endoplasmic reticulum (ER) calcium ATPase 1 (SERCA1), induces severe ER stress-mediated apoptosis in metastatic PTC cells.
PC-23958

SERCA1 inhibitor CKP1

SERCA1 inhibitor

SERCA1 inhibitor CKP1 is a novel specific inhibitor of sarco/endoplasmic reticulum (ER) calcium ATPase 1 (SERCA1), induces severe ER stress-mediated apoptosis in metastatic PTC cells.
PC-23714

Ziconotide acetate

N-type calcium channel antagonist

Ziconotide acetate (SNX-111 acetate) is a potent and selective block of N-type calcium channels antagonist, reduces synaptic transmission.
PC-23713

ZC88

CaV2.2 inhibitor

ZC88 is a selective N-type calcium channel (CaV2.2) blocker, inhibits recombinant human N-type voltage-sensitive calcium channels (α1B/β1b/α2δ) transiently expressed in HEK-293 cells with IC50 of 0.45 uM.
PC-23712

C2230

CaV2.2 inhibitor

C2230 is a potent, specific CaV2.2 (N-type) calcium channel inhibitor/antagonist with IC50 of 1.3 uM (depolarizing Vh of -50 mV), preferably binds to the inactivated CaV2.2 channels.
PC-23650

ML218

T-type calcium channel inhibitor

ML218 (CID 45115620) is a selective, centrally active T-type Ca(2+) channel inhibitor with IC50 of 310 nM and 270 nM for Cav3.2 and Cav3.3 respectively in patch clamp electrophysiology.
PC-23295

Dicoumarol

VRAC inhibitor

Dicoumarol (Dicumarol) is an inhibitor of both NAD(P)H:quinone oxidoreductase 1 (NQO1) and PDK1 with IC50 of 0.37 and 19.42 uM respectively, also is a potent VRAC inhibitor.
PC-23294

SN-89B

LRRC8 inhibitor

SN-89B is a potent LRRC8 channel inhibitorsuppresses agonist-induced platelet activation and aggregation (IC50=840 nM).
PC-23292

SN-406

LRRC8 inhibitor

SN-406 is a potent potent VRAC LRRC8 channels inhibitor with IC50 of 3.1 uM in HEK cells, suppress agonist-induced aggregation, ATP release, and calcium influx.
PC-23040

Nimodipine

L-type calcium channel inhibitor

Nimodipine (BAY-e 9736) is a highly selective inhibitor of L-type voltage-dependent calcium channels (VDCCs), prevents brain damage from reduced blood flow caused by aneurysm.
PC-22420

M201-A

RyR2 inhibitor

M201-A is a potent, selective ryanodine receptor 2 (RyR2) inhibitor, significantly reduces the diastolic Ca2+ in isolated rat ventricular cardiomyocytes, exhibits positive lusi-inotropic effects on rat heart.

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