| Cat. No. |
Product Name |
Information |
| PC-22153 |
TTA-A2
T-type calcium channel inhibitor
|
TTA-A2 is a potent, selective, state-dependent T-type calcium channel antagonist with IC50 of 89 nM and 4100 nM in voltage clamp assays with -80-mV and -100-mV holding membrane potentials in HEK 293 cells heterologously expressing human CaV3.1, respectively. |
| PC-22078 |
MRS1845
SOCE channel inhibitor, Orai1 inhibitor
|
MRS1845 is a selective store-operated Ca2+ channel (SOC) Orai1 inhibitor, inhibits SOC channel-dependent elevations of calcium with IC50 of 1.7 uM in HL-60 cells. |
| PC-21849 |
TTA-Q6
T-type Ca2+ channel inhibitor
|
TTA-Q6 is a potent, selective T-type Ca2+ channel antagonist with IC50 of 14 nM and 590 nM in FLIPR depolarized assaay and FLIPR hyperpolarized assay, respectively. |
| PC-21371 |
S107
RyR2 stabilizer
|
S107 (RyR2 stabilizer) is a specific stabilizing cmpound of Ca2+ release channel ryanodine receptor 2 (RyR2), enhances calstabin2 binding and inhibits Ca2+ leak from mutant RyR2 channels. |
| PC-21312 |
TMDJ-035
RyR2 inhibitor
|
TMDJ-035 is the first highly potent and selective ryanodine receptor 2 (RyR2) inhibitor with EC50 of 13 nM, shows no effect on RyR1 and RyR3. |
| PC-20690 |
Ebselen
VDCC blocker
|
Ebselen (CCG-39161, PI-1005) is a potent voltage-dependent calcium channel (VDCC) blocker, also potently inhibits SARS CoV-2 Mpro with IC50 of 0.67 μM. |
| PC-20657 |
Extracellular vesicle enhancer 634
Extracellular vesicle enhancer
|
Extracellular vesicle enhancer 634 (Compound 634) is a small molecule enhancer of extracellular vesicle (EV) release with immunostimulatory potency via induction of Ca2+ influx, which is mediated by store-operated Ca2+ entry (SOCE). |
| PC-36028 |
SAK3
|
SAK3 (T-VGCC enhancer SAK3) is a potent, orally acitve enhancer of T-type voltage-gated Ca2+ channel (T-VGCC), enhances CaV3.1 and CaV3.3, but not CaV3.2 activity at concentrations of 0.01-10 nM in neuro2A cells in vitro. |
| PC-63283 |
JTV-519 fumarate
|
JTV-519 (K201) is a Ca2+-dependent blocker of SERCA and a partial agonist of ryanodine receptors (RyRs). |
| PC-63282 |
JTV-519 hydrochloride
|
JTV-519 (K201) is a Ca2+-dependent blocker of SERCA and a partial agonist of ryanodine receptors (RyRs). |
| PC-43084 |
Nicardipine hydrochloride
|
Nicardipine(YC-93) is a calcium channel blocker that has been widely used to control blood pressure in severe hypertension following events such as ischemic stroke, traumatic brain injury, and intracerebral hemorrhage.. |
| PC-43083 |
Nicardipine
|
Nicardipine(YC-93) is a calcium channel blocker that has been widely used to control blood pressure in severe hypertension following events such as ischemic stroke, traumatic brain injury, and intracerebral hemorrhage.. |
