| Cat. No. |
Product Name |
Information |
| PC-27044 |
Linoleamide
SERCA inhibitor
|
Linoleamide is an endogenous lipid which is structurally related to sphingosine and sphiganine and closely related with sarco/endoplasmic reticulum Ca2+‐ATPase (SERCA) activity, increases cytosolic Ca2+ levels in MDCK with EC50 of 20 uM. |
| PC-26931 |
2-arachidonoylglycerol
CatSper inhibitor
|
2-arachidonoylglycerol (2-AG) is an endocannabinoid and potent, small molecule sperm calcium channel (CatSper) inhibitor, inhibits ICatSper with IC50 of 350 nM for outward currents and 670 nM for inward currents. |
| PC-26650 |
NDC-1171
SERCA activator
|
NDC-1171 is a potent, selective positive allosteric modulator/ activator of sarcoplasmic/endoplasmic reticulum calcium ATPase (SERCA) pump, improves SERCA-mediated Ca2+ cycling, attenuates cardiac functional decline in mouse model of Duchenne muscular dystrophy (DMD). |
| PC-26379 |
2G272
Ca2+ influx inducer
|
2G272 is a smll molecule calcium (Ca2+) influx inducer, triggers store-operated Ca2+ entry (SOCE) in mBMDC as well as increases in CD80 and CD86 surface expression. |
| PC-25782 |
Diltiazem
L-VDCC inhibitor
|
Diltiazem (CRD-401) is a postsynaptic muscle relaxant that inhibits Ca2+ ions release from sarcoplasmic reticulum stores, inhibits L-type voltage-dependent Ca2+ channels (L-VDCC). |
| PC-25775 |
Pinokalant
ROCC inhibitor
|
Pinokalant (LOE908, LOE-908) is an inhibitor of receptor-operated Ca(2+) channels (ROCCs) and non-selective cation channel inhibitor, inhibits store-operated Ca2+ entry (SOCE) induced by direct depletion of Ca2+ stores with 100 nM thapsigargin or 100 nM ionomycin with EC50 of 2 uM and 4 uM, respectively. |
| PC-25760 |
TMB-8
Ca2+ antagonist
|
TMB-8 is a specific small molecule Ca 2+ antagonist, interferes with Ca2+ availability in smooth and skeletal muscles. |
| PC-24642 |
Gabapentin
Ca2+ channel blocker, TSP-1 inhibitor
|
Gabapentin is a potent, orally active P/Q type Ca2+ channel blocker, inhibits neuronal Ca2+ influx and reduction of neurotransmitter release, Gabapentin can antagonizes the interaction between thrombospondin-1 (TSP1 and its neuronal receptor alpha2delta1. |
| PC-24535 |
Isradipine
Calcium channel blocker
|
Isradipine (PN 200-110) is a non-selective, orally active L-type calcium channel blocker. Is a powerful peripheral vasodilator and calcium antagonist. |
| PC-24336 |
KT-362
Calcium antagonist
|
KT-362 is a small molecule intracellular calcium antagonist, inhibits NE-induced contractions and IP accumulation. |
| PC-23959 |
SERCA1 inhibitor CKP2
SERCA1 inhibitor
|
SERCA1 inhibitor CKP2 is a novel specific inhibitor of sarco/endoplasmic reticulum (ER) calcium ATPase 1 (SERCA1), induces severe ER stress-mediated apoptosis in metastatic PTC cells. |
| PC-23958 |
SERCA1 inhibitor CKP1
SERCA1 inhibitor
|
SERCA1 inhibitor CKP1 is a novel specific inhibitor of sarco/endoplasmic reticulum (ER) calcium ATPase 1 (SERCA1), induces severe ER stress-mediated apoptosis in metastatic PTC cells. |
