| Cat. No. |
Product Name |
Information |
| PC-60582 |
(R)-DRF053 dihydrochloride
CK1/CDK inhibitor
|
(R)-DRF053 dihydrochloride (DRF053) is a potent, cell-permeable, dual CK1/CDK inhibitor with IC50 of 14 nM, 220 nM and 80 nM for CK1, CDK5/p25 and CDK1/cyclin B, respectively. |
| PC-60581 |
Bischof-5
CK1δ inhibitor
|
Bischof-5 (CK1δ inhibitor 5) is a potent, specific casein kinase 1δ (CK1δ) inhibitor with IC50 of 40 nM. |
| PC-60580 |
SR-2890
CK1δ/ε inhibitor
|
SR-2890 is a potent, highly selective casein kinase 1δ/1ε (CK1δ/ε) inhibitor with IC50 of 4 nM for CK1δ. |
| PC-60578 |
SR-653234
CK1δ/ε inhibitor
|
SR-653234 is a purine scaffold casein kinase 1δ/1ε (CK1δ/ε) inhibitor with IC50 of 160/540 nM, respectively. |
| PC-60577 |
CK2 inhibitor D11
CK2α inhibitor
|
CK2 inhibitor D11 is a potent, selective, cell permeab anti-apoptotic protein kinase CK2 with Ki of 5 nM. |
| PC-60387 |
SSTC3
CK1α activator
|
SSTC3 is a novel small-molecule CK1α activator with EC50 of 30 nM (WNT-driven reporter gene assay), Kd of 32 nM. |
| PC-60386 |
VU-WS211
|
A negative control of VU-WS113, which is a potent inhibitor of Wnt signaling with EC50 of 80 nM that selectively potentiates CK1α kinase activity.. |
| PC-60385 |
VU-WS113
Wnt inhibitor
|
VU-WS113 is a potent inhibitor of Wnt signaling with EC50 of 80 nM that selectively potentiates CK1α kinase activity. |
| PC-60383 |
Pyrvinium
CK1α activator
|
Pyrvinium is an anthelmintic effective agent for pinworms that shows to be a potent inhibitor of Wnt signaling with EC50 of 10 nM, binds to all CK1 family members in vitro at low nanomolar concentrations and selectively potentiates CK1α kinase activity. |
| PC-46115 |
Pyrvinium pamoate
CK1α activator
|
Pyrvinium pamoate is an anthelmintic effective agent for pinworms that shows to be a potent inhibitor of Wnt signaling with EC50 of 10 nM, binds to all CK1 family members in vitro at low nanomolar concentrations and selectively potentiates CK1α kinase activity. |
| PC-45871 |
CX4945 sodium
CK2α inhibitor
|
Silmitasertib (CX4945) sodium is a potent, selective, orally bioavailable, ATP-competitive inhibitor of protein kinase CK2 with Ki of 0.38 nM, CK2α IC50 of 1 nM. |
| PC-45870 |
CX4945
CK2α inhibitor
|
CX-4945 (Silmitasertib, CX4945) is a potent, selective, orally bioavailable, ATP-competitive inhibitor of protein kinase Casein Kinase 2 (CK2) with Ki of 0.38 nM, CK2α IC50 of 1 nM. |
