| Cat. No. |
Product Name |
Information |
| PC-22273 |
ARC-3140
CK2 inhibitor
|
ARC-3140 is a potent, selective bisubstrate inhibitor of protein kinase CK2 (Casein kinase II) with Ki of 84 pM, addressing the ATP site and the substrate-binding site of CK2, interferes with both sub-interfaces of the bipartite CK2α/CK2β interaction. |
| PC-22272 |
ARC-1502
CK2 inhibitor
|
ARC-1502 is a potent, selective bisubstrate inhibitor of protein kinase CK2 (Casein kinase II) with Ki of 0.56 nM, addressing the ATP site and the substrate-binding site of CK2. interferes with both sub-interfaces of the bipartite CK2α/CK2β interaction. |
| PC-22047 |
CK2 inhibitor 7h
CK2 inhibitor
|
CK2 inhibitor 7h is a potent, selective Casein Kinase 2 (CK2) inhibitor with IC50 of <3 nM and SPR KD of 6.33 pM, pAKTS129 IC50 of 4 nM. |
| PC-21783 |
AB668
CK2 inhibitor
|
AB668 is a selective, bivalent Casein Kinase 2 (CK2) inhibitor targeting the ATP site and the αD pocket, AB668 inhibits the CK2 holoenzyme with Ki value of 41 nM (IC50=65 nM). |
| PC-21547 |
CKR-49-17
CK1γ2 activator
|
CKR-49-17 is a potent, allosteric small molecule activator of CK1γ2 with Kd value of 180 nM in MST assays. |
| PC-20908 |
SGC-CK2-1 analog 2h
CK2α inhibitor
|
SGC-CK2-1 analog 2h is potent, selective and in vivo active inhibitor of casein kinase 2α (CSNK2A, CK2α) with pIC50 of 7.5 and 7.7 against CSNK2A1 and CSNK2A2, respectively. |
| PC-20823 |
SR-4133
CK1ε inhibitor
|
SR-4133 (SR4133) is a potent and highly selective CK1ε isoform inhibitor with IC50 of 58 nM, no significant acitivity agianst CK1δ (IC50>10,000 nM). |
| PC-49496 |
PF670462
CK1ε/CK1δ inhibitor
|
PF-670462 (PF670462) is a potent and selective inhibitor casein kinase CK1ε and CK1δ with IC50 of 7.7 nM and 14 nM, respectively, causes a significant phase delay in animal models of circadian rhythm. |
| PC-38526 |
Epiblastin A
CK1 inhibitor
|
Epiblastin A is a small molecule ATP-competitive casein kinases 1 (CK1) inhibitor with IC50 values of 0.8, 3.7 and 3.8 uM for CK1δ, CK1ε and CK1α, engages CK1 isoenzymes in cell lysate and induces efficient conversion of mouse epiblast stem cells (EpiSCs) to embryonic stem cells (cESCs). |
| PC-35615 |
BMS-211
|
BMS-211 is a prodrug of the parent pan-CK2 inhibitor BMS-699.. |
| PC-35614 |
BMS-595
|
BMS-595 (BMS595) is a novel potent, selective, ATP-competitive casein kinase 2 (CK2) inhibitor with IC50 of 1.3 nM (CKα). |
| PC-60384 |
Pyrvinium Iodide
|
An anthelmintic effective for pinworms that shows to be a potent inhibitor of Wnt signaling with EC50 of 10 nM, binds to all CK1 family members in vitro at low nanomolar concentrations and selectively potentiates CK1α kinase activity. |
