| Cat. No. |
Product Name |
Information |
| PC-46115 |
Pyrvinium pamoate
Wnt inhibitor, CK1α activator
|
Pyrvinium pamoate is an anthelmintic effective agent for pinworms that shows to be a potent inhibitor of Wnt signaling with EC50 of 10 nM, binds to all CK1 family members in vitro at low nanomolar concentrations and selectively potentiates CK1α kinase activity. |
| PC-45871 |
CX4945 sodium
CK2α inhibitor
|
Silmitasertib (CX4945) sodium is a potent, selective, orally bioavailable, ATP-competitive inhibitor of protein kinase CK2 with Ki of 0.38 nM, CK2α IC50 of 1 nM. |
| PC-45870 |
CX4945
CK2α inhibitor
|
CX-4945 (Silmitasertib, CX4945) is a potent, selective, orally bioavailable, ATP-competitive inhibitor of protein kinase Casein Kinase 2 (CK2) with Ki of 0.38 nM, CK2α IC50 of 1 nM. |
| PC-42523 |
D4476
CK1 inhibitor
|
D4476 (Casein Kinase I Inhibitor, D 4476, D-4476) is a potent, selective ATP-competitive inhibitor of CK1 with IC50 of 0.3 uM in vitro. |
| PC-42026 |
SR-3029
CK1δ/ε inhibitor
|
SR-3029 is a potent, highly selective, ATP-competitive and brain penetrating Casein Kinase 1δ/ε (CK1δ/ε) inhibitor with IC50 of 44/260 nM, respectively. |
| PC-42058 |
TA-01
CK1δ/ε inhibitor, p38α inhibitor
|
TA-01 is a potent inhibitor of Casein Kinase CK1ε, CK1δ and p38α with IC50 of 6.4, 6.8 and 6.7 nM, respectively. |
| PC-25590 |
CK1γ inhibitor 1h
CK1γ inhibitor
|
CK1γ inhibitor 1h is a potent, selective inhibitor of casein kinase 1γ (CK1γ) with IC50 of 18 nM, has >100-fold selective over CK1α, CK1δ and GSK3β, inhibits phosphorylation of LRP6 in HEK293 cell with IC50 of 0.7 uM. |
| PC-25589 |
FP1-24
CK1γ inhibitor
|
FP1-24 (CK1γ Inhibitor 13) is a potent and selective CK1γ inhibitor with IC50 of 5 nM, with 8- and 50-fold selective over CK1δ and CK1α respectively, and shows activity against GSK3β. |
| PC-25588 |
SGC-CK1γ-1
CK1γ inhibitor
|
SGC-CK1γ-1 is the first chemical probe inhibitor of casein kinase 1γ (CK1γ) subfamily (CK1γ1, CK1γ2, and CK1γ3) with IC50 of 180,180 and 230 nM in NanoBRET assays respectively, inhibits both WNT signaling and human cytomegalovirus replication. |
| PC-25510 |
CK2 inhibitor TBB
CK2 inhibitor
|
TBB (4,5,6,7-tetrabromobenzotriazole) is a potent, cell-permeable and ATP-competitive CK2 inhibitor with IC50 of 0.15 uM and 1.6 uM for rat liver CK2 and human CK2 respectively. |
| PC-25109 |
IOR-160
CK2/HDAC inhibitor
|
IOR-160 is a potent dual inhibitor of casein kinase 2 (CK2) and HDAC with IC50 of 1.7 nM for CK2 and 3.3/24.0/3.9/13.0 nM for HDAC1/2/3/6 respectively. |
| PC-24756 |
CK2 bivalent inhibitor Biv5
CK2 inhibitor
|
CK2 bivalent inhibitor Biv5 is a picomolar bivalent inhibitor of protein casein kinase 2 (CK2) with IC50 of 51 pM (CK2α), shows potent antiviral activity against SARS-CoV-2 in HEK-ACE2-TMPRSS2 and Vero cells. |
