| Cat. No. |
Product Name |
Information |
| PC-60383 |
Pyrvinium
CK1α activator
|
Pyrvinium is an anthelmintic effective agent for pinworms that shows to be a potent inhibitor of Wnt signaling with EC50 of 10 nM, binds to all CK1 family members in vitro at low nanomolar concentrations and selectively potentiates CK1α kinase activity. |
| PC-46115 |
Pyrvinium pamoate
Wnt inhibitor, CK1α activator
|
Pyrvinium pamoate is an anthelmintic effective agent for pinworms that shows to be a potent inhibitor of Wnt signaling with EC50 of 10 nM, binds to all CK1 family members in vitro at low nanomolar concentrations and selectively potentiates CK1α kinase activity. |
| PC-45871 |
CX4945 sodium
CK2α inhibitor
|
Silmitasertib (CX4945) sodium is a potent, selective, orally bioavailable, ATP-competitive inhibitor of protein kinase CK2 with Ki of 0.38 nM, CK2α IC50 of 1 nM. |
| PC-45870 |
CX4945
CK2α inhibitor
|
CX-4945 (Silmitasertib, CX4945) is a potent, selective, orally bioavailable, ATP-competitive inhibitor of protein kinase Casein Kinase 2 (CK2) with Ki of 0.38 nM, CK2α IC50 of 1 nM. |
| PC-42523 |
D4476
CK1 inhibitor
|
D4476 (Casein Kinase I Inhibitor, D 4476, D-4476) is a potent, selective ATP-competitive inhibitor of CK1 with IC50 of 0.3 uM in vitro. |
| PC-42026 |
SR-3029
CK1δ/ε inhibitor
|
SR-3029 is a potent, highly selective, ATP-competitive and brain penetrating Casein Kinase 1δ/ε (CK1δ/ε) inhibitor with IC50 of 44/260 nM, respectively. |
| PC-42058 |
TA-01
CK1δ/ε inhibitor, p38α inhibitor
|
TA-01 is a potent inhibitor of Casein Kinase CK1ε, CK1δ and p38α with IC50 of 6.4, 6.8 and 6.7 nM, respectively. |
| PC-26004 |
BMS-159
CK2 inhibitor
|
BMS-159 is the orally bioavailabile phosphate prodrug of BMS-135, which is a potent, ATP-competitive inhibitor of Casein kinase 2 (CK2), exhibits subnanomolar potency against both CK2α and CK2α′ isoforms with IC50 of 0.8 nM and 0.3 nM, respectively. |
| PC-26003 |
BMS-135
CK2 inhibitor
|
BMS-135 is a potent, ATP-competitive inhibitor of Casein kinase 2 (CK2), exhibits subnanomolar potency against both CK2α and CK2α′ isoforms with IC50 of 0.8 nM and 0.3 nM, respectively. |
| PC-25908 |
IGS-2.7
CK1δ inhibitor
|
IGS-2.7 is a potent, selective and brain permeable CK1delta (CK-1δ, CK1δ) inhibitor with IC50 of 23 nM, >35-fold selective over CK1ε (IC50=840 nM). |
| PC-25590 |
CK1γ inhibitor 1h
CK1γ inhibitor
|
CK1γ inhibitor 1h is a potent, selective inhibitor of casein kinase 1γ (CK1γ) with IC50 of 18 nM, has >100-fold selective over CK1α, CK1δ and GSK3β, inhibits phosphorylation of LRP6 in HEK293 cell with IC50 of 0.7 uM. |
| PC-25589 |
FP1-24
CK1γ inhibitor
|
FP1-24 (CK1γ Inhibitor 13) is a potent and selective CK1γ inhibitor with IC50 of 5 nM, with 8- and 50-fold selective over CK1δ and CK1α respectively, and shows activity against GSK3β. |
