| Cat. No. |
Product Name |
Information |
| PC-22273 |
ARC-3140
CK2 inhibitor
|
ARC-3140 is a potent, selective bisubstrate inhibitor of protein kinase CK2 (Casein kinase II) with Ki of 84 pM, addressing the ATP site and the substrate-binding site of CK2, interferes with both sub-interfaces of the bipartite CK2α/CK2β interaction. |
| PC-22272 |
ARC-1502
CK2 inhibitor
|
ARC-1502 is a potent, selective bisubstrate inhibitor of protein kinase CK2 (Casein kinase II) with Ki of 0.56 nM, addressing the ATP site and the substrate-binding site of CK2. interferes with both sub-interfaces of the bipartite CK2α/CK2β interaction. |
| PC-22047 |
CK2 inhibitor 7h
CK2 inhibitor
|
CK2 inhibitor 7h is a potent, selective Casein Kinase 2 (CK2) inhibitor with IC50 of <3 nM and SPR KD of 6.33 pM, pAKTS129 IC50 of 4 nM. |
| PC-21547 |
CKR-49-17
CK1γ2 activator
|
CKR-49-17 is a potent, allosteric small molecule activator of CK1γ2 with Kd value of 180 nM in MST assays. |
| PC-20908 |
SGC-CK2-1 analog 2h
CK2α inhibitor
|
SGC-CK2-1 analog 2h is potent, selective and in vivo active inhibitor of casein kinase 2α (CSNK2A, CK2α) with pIC50 of 7.5 and 7.7 against CSNK2A1 and CSNK2A2, respectively. |
| PC-20823 |
SR-4133
CK1ε inhibitor
|
SR-4133 (SR4133) is a potent and highly selective CK1ε isoform inhibitor with IC50 of 58 nM, no significant acitivity agianst CK1δ (IC50>10,000 nM). |
| PC-35615 |
BMS-211
|
BMS-211 is a prodrug of the parent pan-CK2 inhibitor BMS-699.. |
| PC-60384 |
Pyrvinium Iodide
|
An anthelmintic effective for pinworms that shows to be a potent inhibitor of Wnt signaling with EC50 of 10 nM, binds to all CK1 family members in vitro at low nanomolar concentrations and selectively potentiates CK1α kinase activity. |
