Cat. No. |
Product Name |
Information |
PC-42237 |
4E2RCat
eIF4E/eIF4G inhibitor
|
4E2RCat is a small molecule inhibitor of eIF4E-eIF4G interaction with IC50 of 13.5 uM in TR-FRET-based assay. |
PC-45737 |
4EGI-1
eIF4E/eIF4G inhibitor
|
4EGI-1 is a competitive eIF4E/eIF4G interaction inhibitor with Kd of 25 uM (binding to eIF4E). |
PC-23798 |
Salubrinal
eIF2α dephosphorylation inhibitor
|
Salubrinal is a selective inhibitor of eukaryotic translation initiation factor 2 subunit alpha (eIF2alpha, eIF2α) dephosphorylation, also is a potential inhibitor of dual-specificity phosphatase 2 (Dusp2). |
PC-23755 |
Girolline
eIF5A modulator
|
Girolline (Girodazole) is a sequence-selective modulator of translation factor eIF5A, interferes with ribosome-eIF5A interaction and induces ribosome stalling, an anti-tumor agent as well as having activity against malaria. |
PC-22415 |
CR-1-31-B
eIF4A inhibitor
|
CR-1-31-B (CR-31) is a potent and specific eIF4A RNA helicase inhibitor, blocks translation of the MUC1-C oncoprotein. |