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Cat. No. Product Name Information
PC-42237

4E2RCat

eIF4E/eIF4G inhibitor

4E2RCat is a small molecule inhibitor of eIF4E-eIF4G interaction with IC50 of 13.5 uM in TR-FRET-based assay.
PC-45737

4EGI-1

eIF4E/eIF4G inhibitor

4EGI-1 is a competitive eIF4E/eIF4G interaction inhibitor with Kd of 25 uM (binding to eIF4E).
PC-23798

Salubrinal

eIF2α dephosphorylation inhibitor

Salubrinal is a selective inhibitor of eukaryotic translation initiation factor 2 subunit alpha (eIF2alpha, eIF2α) dephosphorylation, also is a potential inhibitor of dual-specificity phosphatase 2 (Dusp2).
PC-23755

Girolline

eIF5A modulator

Girolline (Girodazole) is a sequence-selective modulator of translation factor eIF5A, interferes with ribosome-eIF5A interaction and induces ribosome stalling, an anti-tumor agent as well as having activity against malaria.
PC-22415

CR-1-31-B

eIF4A inhibitor

CR-1-31-B (CR-31) is a potent and specific eIF4A RNA helicase inhibitor, blocks translation of the MUC1-C oncoprotein.

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