| Cat. No. |
Product Name |
Information |
| PC-24078 |
Ferfluor-1
Ferroptosis inhibitor
|
Ferfluor-1 is a potent, selective ferroptosis inhibitor, rescues ferroptotic cell death on HT1080 cells with EC50 of 57 nM, also is a specific ferroptosis photoluminescence imaging probe. |
| PC-22833 |
NCOA4-FTH1 inhibitor 9a
NCOA4-FTH1 inhibitor
|
NCOA4-FTH1 inhibitor 9a is a new ferroptosis inhibitor through disrupting the NCOA4-FTH1 protein-protein interaction, reduces intracellular ferrous iron, inhibits Erastin-induced ferroptosiswith EC50 of 0.29 μM in HT22 cells. |
| PC-22532 |
SRS 16-86
Ferroptosis inhibitor
|
SRS16-86 is a potent inhibitor of ferroptosis. |
| PC-22475 |
BCP-T.A
Ferroptosis inducer
|
BCP-T.A is a potent ferroptosis inducer by binding to GPX4 with IC50 of 17 nM in ferroptosis sensitive cell line NCI-H522. |
| PC-22423 |
Erastin
Ferroptosis inducer
|
Erastin is a specific ferroptosis-inducing compound, shows RAS-selective lethality, also targetsvoltage-dependent anion channel 3 (VDAC3). |
| PC-21713 |
GPX4 inhibitor A16
GPX4 inhibitor
|
GPX4 inhibitor A16 (GPX4-IN-9) is a potent, selective and covalent inhibitor of glutathione peroxidase 4 (GPX4), shows potent anti-proliferation activity the pancreatic cancer cell line AsPC-1 with IC50 of 22 nM. |
| PC-20966 |
icFSP1
FSP1 inhibitor
|
icFSP1 is a potent, selective human ferroptosis suppressor protein-1 (hFSP1) inhibitor, promotes ferroptosis and indirectly inhibits FSP1 by inducing condensate formation. |
| PC-20924 |
FerroLOXIN-2
Ferroptosis inhibitor
|
FerroLOXIN-2 is a specific, small-molecule inhibitor of ferroptosis, inhibits 15LOX/PEBP1 catalytic complex rather than 15LOX alone, effectively suppresses ferroptosis in vitro and in vivo. |
| PC-20923 |
FerroLOXIN-1
Ferroptosis inhibitor, 15LOX/PEBP1 inhibitor
|
FerroLOXIN-1 is a specific, small-molecule inhibitor of ferroptosis, inhibits 15LOX/PEBP1 catalytic complex rather than 15LOX alone, effectively suppresses ferroptosis in vitro and in vivo. |
| PC-20811 |
FSEN1
FSP1 inhibitor
|
FSEN1 (Ferroptosis Sensitizer 1) is a specific small molecule, uncompetitive inhibitor of ferroptosis suppressor protein 1 (FSP1) with IC50 of 133 nM, sensitizes cancer cells to ferroptosis. |
| PC-20810 |
AKI-02
Ferroptosis inhibitor
|
AKI-02 is a hydroxypyridinone-based iron chelator, potently inhibits labile iron-mediated ferroptosis. |
| PC-20267 |
GPX4 inhibitor 24
GPX4 inhibitor
|
GPX4 inhibitor 24 is a potent glutathione peroxidase 4 (GPX4) inhibitor, induces ferroptosis in vivo. |
