| Cat. No. |
Product Name |
Information |
| PC-43024 |
AMG-3969
GK-GKRP inhibitor
|
AMG-3969 is a potent, metabolically stable Glucokinase (GK)-GKRP (GK regulatory protein) disruptor with IC50 of 4 nM, does not block the GK binding site directly. |
| PC-61880 |
PF-04991532
Glucokinase activator
|
PF-04991532 (PF4991532) is a potent, hepatoselective Glucokinase (GK) activator with EC50 of 90±45 nM. |
| PC-61879 |
MK-0941 mesylate
Glucokinase activator
|
MK-0941 mesylate (MK0941) is a novel potent, orally active Glucokinase (GK) activator with EC50 of 0.240 and 0.065 uM in 2.5 and 10 mM glucose, respectively. |
| PC-61878 |
MK-0941
Glucokinase activator
|
MK-0941 (MK0941) is a potent, orally active Glucokinase (GK) activator with EC50 of 0.240 and 0.065 uM in 2.5 and 10 mM glucose, respectively. |
| PC-61877 |
AZD1092
Glucokinase activator
|
AZD1092 (GKA-80) is a potent Glucokinase (GK) activator with EC50 of 30 nM. |
| PC-61876 |
PSN-GK1
Glucokinase activator
|
PSN-GK1 is a potent, orally available Glucokinase (GK) activator with EC50 of 130 nM at 5 mM glucose (4.3-fold). |
| PC-61875 |
Piragliatin
Glucokinase activator
|
Piragliatin (RO 4389620, R-1440) is an allosteric, potent Glucokinase (GK) activator with SC1.5 of 0.18 uM. |
| PC-61099 |
AM-9514
Glucokinase activator
|
AM-9514 is a potent glucokinase (GK) activator with EC50 of 0.29 uM. |
| PC-60040 |
Dorzagliatin
Glucokinase activator
|
Dorzagliatin (HMS-5552, HMS5552) is a novel potent, fourth-generation glucokinase (GK) activator. |
| PC-42091 |
AM-2394
Glucokinase activator
|
AM-2394 (AM2394) is a potent, orally bioavailable Glucokinase (GK) activator with EC50 of 60 nM. |
| PC-42677 |
Ro 28-1675
Glucokinase activator
|
Ro 28-1675 is a potent, allosteric activator of Glucokinase (GK) with SC1.5 of 0.24 uM. |
