| Cat. No. |
Product Name |
Information |
| PC-61878 |
MK-0941
Glucokinase activator
|
MK-0941 (MK0941) is a potent, orally active Glucokinase (GK) activator with EC50 of 0.240 and 0.065 uM in 2.5 and 10 mM glucose, respectively. |
| PC-61877 |
AZD1092
Glucokinase activator
|
AZD1092 (GKA-80) is a potent Glucokinase (GK) activator with EC50 of 30 nM. |
| PC-61876 |
PSN-GK1
Glucokinase activator
|
PSN-GK1 is a potent, orally available Glucokinase (GK) activator with EC50 of 130 nM at 5 mM glucose (4.3-fold). |
| PC-60040 |
Dorzagliatin
Glucokinase activator
|
Dorzagliatin (HMS-5552, HMS5552) is a novel potent, fourth-generation glucokinase (GK) activator. |
| PC-42091 |
AM-2394
Glucokinase activator
|
AM-2394 (AM2394) is a potent, orally bioavailable Glucokinase (GK) activator with EC50 of 60 nM. |
| PC-42677 |
Ro 28-1675
Glucokinase activator
|
Ro 28-1675 is a potent, allosteric activator of Glucokinase (GK) with SC1.5 of 0.24 uM. |
| PC-49836 |
LY2608204
Glucokinase activator
|
Globalagliatin (LY2608204) is a potent, small molecule activator of glucokinase (GK) with EC50 value of 42 nM, induces glucose metabolism and reduces glucose levels for the treatment of type 2 diabetes. |
| PC-49835 |
PF-04937319
Glucokinase activator
|
PF-04937319 (PB-201, PF 4937319) is a partial, pancreas/liver-dual glucokinase activator with EC50 of 174 nM, induces glucose metabolism and reduces glucose levels for the treatment of type 2 diabetes. |
| PC-35647 |
Sinogliatin
|
Sinogliatin (Dorzagliatin, HMS-5552, RO-5305552) is a novel, first-in-class glucokinase activator (GKS) to treat diabetes mellitus.. |
| PC-61875 |
Piragliatin
|
Piragliatin (RO 4389620. |
| PC-61099 |
AM-9514
|
A potent gucokinase (GK) activator with EC50 of 0.29 uM. |
