| Cat. No. |
Product Name |
Information |
| PC-72601 |
GSK3640254
HIV-1 maturation inhibitor
|
GSK3640254 (GSK254, Fipravirimat) is a novel potent HIV-1 maturation inhibitor with EC90 of 33 nM against a minilibrary of clinically relevant HIV-1 polymorphisms in a multiple-cycle assay. |
| PC-38204 |
FC-8052
HIV-1 Nef inhibitor
|
FC-8052 (FC8052) is a highly potent inhibitor of HIV-1 Nef-effector kinase, binds to recombinant Nef in vitro with Kd of 10 pM. |
| PC-38203 |
SRI-37264
HIV-1 Nef inhibitor
|
SRI-37264 (SRI 37264) is a small molecule inhibitor of HIV-1 Nef-mediated activation of the myeloid Src-family kinase Hck, blocks HIV-1 replication in macrophages and disrupts MHC-I downregulation. |
| PC-36113 |
ZBMA-1
HIV-1 Vif inhibitor
|
ZBMA-1 is a potent HIV-1 replication inhibitor (IC50=1.01 uM) that efficiently protects APOBEC3G protein by targeting Vif-APOBEC3G complex. |
| PC-36055 |
ABX464
|
Obefazimod (ABX464) is a novel class of anti-HIV small molecule targeting Rev-mediated viral RNA biogenesis, shows dose dependent inhibition of HIV-1 replication in stimulated PBMCs with IC50 of 0.1-0.5 uM. |
| PC-35935 |
BMS-818251
HIV-1 inhibitor
|
BMS-818251 (BMS818251) is a novel potent, small-molecule inhibitor of HIV-1 entry with EC50 of 0.019 nM against e laboratory-adapted HIV-1 strain NL4-3. |
| PC-35869 |
GS-6207
HIV-1 capsid inhibitor
|
GS-6207 (GS6207, GS-CA1, Lenacapavir) is a potent, selective inhibitor of HIV-1 capsid function with potency and potential to be clinically effective against a broad range of HIV-1 strains. |
| PC-35751 |
NSC260594
|
NSC260594 (NSC 260594) is a specific inhibitor of HIV-1 RNA packaging, which involves preventing the interaction of Gag with SL3 by stabilizing this small RNA stem-loop which then leads to stabilization of the global packaging signal region (psi or ψ). |
| PC-35225 |
NBD-14189
|
NBD-14189 (NBD14189) is a novel potent HIV-1 entry antagonist with potency as low as 63 nM against some clinical isolates, target HIV-1 gp120.. |
| PC-35156 |
KNI-1657
HIV-1 protease inhibitor
|
KNI-1657 (KNI1657) is a highly potent HIV-1 protease inhibitor (97% inhibition at 1 nM) with high sensitivity against lopinavir/ritonavir- or darunavir-resistant strains. |
| PC-43512 |
TAK-779
CCR5 antagonist
|
TAK-779 is a potent, specific, nonpeptide CCR5 antagonist with Kd of 0.45 nM, antagonizes CCR2b to a lesser extent (27 nM) but does not affect CCR1, CCR3, or CCR4. |
| PC-43481 |
MK-2048
HIV-1 integrase inhibitor
|
MK-2048 is a potent inhibitor of HIV-1 integrase (IN) and IN mutant R263K with IC50 of 2.6 nM and 1.5 nM, respectively. |
