| Cat. No. |
Product Name |
Information |
| PC-63542 |
PF-3450074
HIV capsid inhibitor
|
PF-3450074 (PF74) is a small molecule HIV capsid protein, destabilized the viral capsid in vitro. |
| PC-63540 |
GS-9695
HIV integrase inhibitor
|
GS-9695 is a potent, non-catalytic site HIV integrase inhibitor with wild type EC50 of 1.2 nM. |
| PC-63539 |
GS-9822
HIV integrase inhibitor
|
GS-9822 (GS9822) is a potent, non-catalytic site HIV integrase inhibitor with wild type EC50 of 3 nM, potently inhibits the LEDGF/p75-integrase interaction with IC50 of 70 nM. |
| PC-43448 |
BMS-707035
|
BMS-707035 is a potent, specific, and reversible HIV-I integrase (IN) inhibitor that blocks HIV IN strand transfer activity with IC50 of 15 nM.. |
| PC-63384 |
GSK2838232
HIV maturation inhibitor
|
GSK-2838232 is a novel HIV maturation inhibitor being developed for the treatment of HIV in combination with other antiretroviral therapy.. |
| PC-43417 |
Dolutegravir
|
Dolutegravir (GSK1349572) is a potent, next-generation HIV integrase (IN) inhibitor, inhibits HIV-1 integrase-catalyzed strand transfer with IC50 of 2.7 nM. |
| PC-62902 |
IC-9564
HIV entry inhibitor
|
IC-9564 (AIDS033640) is a betulinic acid derivative and potent HIV entry inhibitor that blocks HIV-1 envelope-mediated membrane fusion with IC90 of 0.22 uM for NL4-3 strain. |
| PC-62901 |
YIR-821
CD4 mimic, HIV inhibitor
|
YIR-821 is a small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 2.8 uM against YTA48P virus with no significant cytotoxicity (CC50>200 uM). |
| PC-62899 |
HAR-171
CD4 mimic
|
HAR-171 is a small molecule CD4 mimic and gp120-CD4 blocker that acts as a highly potent HIV entry inhibitor with IC50 of 0.43 uM against YTA48P virus with no significant cytotoxicity (CC50>120 uM). |
| PC-62898 |
YYA-021
gp120-CD4 inhibitor
|
YYA-021 is a small-molecule gp120-CD40 blocker that acts as a highly potent HIV entry inhibitor with IC50 of 9 uM against YTA48P virus with no significant cytotoxicity. |
| PC-62831 |
GSK-8999
HIV-1 maturation inhibitor
|
GSK-8999 (GSK-2578999) is a novel, potent HIV-1 maturation inhibitor with IC50 values of 17 nM, 23 nM, 25 nM, and 8 nM for wild type, Q369H, V370A, and T371A respectively. |
| PC-62712 |
RN-18
|
RN-18 is a small molecule that antagonizes HIV-1 Vif function and inhibits HIV-1 replication only in the presence of A3G. |
