Cat. No. |
Product Name |
Information |
PC-42661 |
Rilpivirine
NNRTI
|
Rilpivirine (R278474, TMC278) is a highly potent nonnucleoside inhibitor (NNRTI) of HIV-1 reverse trK7912:M7912anscriptase with IC50 of 0.4 nM for WT HIV-1 in cell-based assay. |
PC-42660 |
Efavirenz
NNRTI
|
Efavirenz (DMP 266, EFV) is a highly potent nonnucleoside inhibitor (NNRTI) of HIV-1 reverse transcriptase with Ki of 2.93 nM for WT HIV-1 RT. |
PC-45186 |
Atazanavir
HIV-1 protease inhibitor
|
Atazanavir (BMS-232632) is a highly potent HIV-1 protease inhibitor that exhibits potent anti-HIV activity EC50 of 2.6-5.3 nM and EC90 of 9-15 nM in cell culture. |
PC-42793 |
BMS-538203
|
BMS-538203 is a chemical intermidate of BMS-626529, a HIV-1 attachment inhibitor that targets gp120. |
PC-22328 |
Bevirimat
HIV-1 maturation inhibitor
|
Bevirimat (PA-457) is a potent HIV inhibitor that inhibits HIV Gag protein processing and viral maturation. |
PC-22327 |
JRC-II-191
CD4 mimic
|
JRC-II-191 is a small-molecule CD4 mimic with Kd of 760 nM for gp120 envelope glycoprotein, inhibits HIV-1 entry by blocking the binding of the HIV-1 envelope glycoprotein gp120 to the CD4 receptor. |
PC-22321 |
Lamivudine
NRTI
|
Lamivudine (BCH-189) is an orally active nucleoside reverse transcriptase inhibitor (NRTI), inhibits HIV reverse transcriptase and also the reverse transcriptase of HBV, also inhibits long interspersed nuclear element-1 (LINE-1 or L1) reverse transcriptase. |
PC-21968 |
Bavtavirine
NNRTI
|
Bavtavirine is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) against HIV-1. |
PC-21806 |
Cabotegravir
HIV-1 integrase inhibitor
|
Cabotegravir (GSK-1265744) is a potent, selective HIV-1 integrase inhibitor with IC50 of 3 nM in biochemical integrase strand transfer assay (INST). |
PC-21801 |
GS-9770
HIV-1 protease inhibitor
|
GS-9770 is a potent, selective, non-peptidomimetic and orally active HIV protease inhibitor with Ki(app) value of 0.16 nM (recombinant HIV-1 PR). |
PC-21700 |
Lopinavir
HIV-1 protease inhibitor
|
Lopinavir (ABT-378) is a highly potent inhibitor of HIV-1 protease with Ki of 1.3 to 3.6 pM for wild-type and mutant HIV protease. |
PC-21699 |
Tipranavir
HIV-1 protease inhibitor
|
Tipranavir (PNU-140690) is a potent, nonpeptidic and orally bioavailable HIV protease inhibitor with Ki vaule of 8 pM, shows an IC90 value of 100 nM in antiviral cell culture. |