| Cat. No. |
Product Name |
Information |
| PC-38203 |
SRI-37264
HIV-1 Nef inhibitor
|
SRI-37264 (SRI 37264) is a small molecule inhibitor of HIV-1 Nef-mediated activation of the myeloid Src-family kinase Hck, blocks HIV-1 replication in macrophages and disrupts MHC-I downregulation. |
| PC-36158 |
HIV-1 inhibitor 5b
HIV-1 inhibitor
|
HIV-1 inhibitor 5b is a novel anti-HIV-1 compound that inhibits HIV-1 JR-CSF with EC50 of 1 nM without significant cytotoxicity (CC50>20 uM), also shows potency against NRTI- and NNRTI-resistant HIV-1 (EC50=1-3 nM). |
| PC-36113 |
ZBMA-1
HIV-1 Vif inhibitor
|
ZBMA-1 is a potent HIV-1 replication inhibitor (IC50=1.01 uM) that efficiently protects APOBEC3G protein by targeting Vif-APOBEC3G complex. |
| PC-36055 |
ABX464
|
Obefazimod (ABX464) is a novel class of anti-HIV small molecule targeting Rev-mediated viral RNA biogenesis, shows dose dependent inhibition of HIV-1 replication in stimulated PBMCs with IC50 of 0.1-0.5 uM. |
| PC-35935 |
BMS-818251
HIV-1 inhibitor
|
BMS-818251 (BMS818251) is a novel potent, small-molecule inhibitor of HIV-1 entry with EC50 of 0.019 nM against e laboratory-adapted HIV-1 strain NL4-3. |
| PC-35869 |
Lenacapavir
HIV-1 capsid inhibitor
|
Lenacapavir (GS6207, GS-CA1) is a potent, selective inhibitor of HIV-1 capsid function, shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells. |
| PC-35751 |
NSC260594
HIV-1 inhibitor
|
NSC260594 (NSC 260594) is a specific inhibitor of HIV-1 RNA packaging, which involves preventing the interaction of Gag with SL3 by stabilizing this small RNA stem-loop which then leads to stabilization of the global packaging signal region (psi or ψ). |
| PC-35229 |
1E7-03
HIV inhibitor
|
1E7-03 is a small molecule targeting the RVxF interacting site on PP1, inhibits HIV-1, Ebolavirus (EBOV), and Venezuelan equine encephalitis virus (VEEV, EC50=0.6 uM). |
| PC-35228 |
BNM-III-170
CD4 mimic, HIV inhibitor
|
BNM-III-170 is a small-molecule CD4-mimetic compound that enhances vaccine efficacy against HIV-1 challenge in vivo. |
| PC-35227 |
BNM-III-170 trifluoroacetate
CD4 mimic, HIV inhibitor
|
BNM-III-170 TFA salt is a small-molecule CD4-mimetic compound that enhances vaccine efficacy against HIV-1 challenge in vivo. |
| PC-35225 |
NBD-14189
|
NBD-14189 (NBD14189) is a novel potent HIV-1 entry antagonist with potency as low as 63 nM against some clinical isolates, target HIV-1 gp120.. |
| PC-35158 |
IMB-301
HIV-1 Vif inhibitor
|
IMB-301 (NSC 301209) is a small molecule inhibitor that target the binding interface of the HIV-1 Vif/hA3G complex, inhibits the replication of HIV-1 in H9 cells (IC50=8.63 uM). |
