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Cat. No. Product Name Information
PC-25019

Suricapavir

HIV-1 integrase inhibitor

Suricapavir is a potent, selective HIV-1 integrase inhibitor.
PC-24934

MK-8527

HIV-1 RT inhibitor

MK-8527 is a potent, long-acting and orally active HIV inhibitor and nucleoside reverse transcriptase translocation inhibitor (NRTTI).
PC-24825

BIT225

HIV-1 Vpu inhibitor

BIT225 (BIT-225) is a specific small molecule inhibitor of HIV-1 Vpu ion channel activity, inhibits the release of HIV-1 in human MDM with EC50 of 2.25 uM.
PC-24720

NNRTI compound 5i3

NNRTI

NNRTI compound 5i3 is a highly potent HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI), shows potent antiviral activity against NNRTI-resistant strains (GH9, p1579, p5375, p1833, and p5735) with EC50 of 2.6-18.3 nM.
PC-24427

ZK-316

NNRTI

ZK-316 is a potent, HIV non-nucleoside reverse transcriptase inhibitor (NNRTI) with IC50 of 0.21 uM (WT HIV-1 RT), exhibits potent and broad-spectrum activity against wild-type and clinically observed mutant strains with EC50 of 0.99-75.1 nM.
PC-24020

RDS1759

HIV-1 RNase H inhibitor

RDS1759 is a specific small molecule inhibitor of HIV-1 RT-associated RNase H activity with IC50 of 8.6 uM (mutated HIV-1 RT R448A), inhibits viral inhibition rate with IC50 of 0.17 uM.
PC-23799

HIV-1 nuclear import inhibitor H27

HIV-1 nuclear import inhibitor

HIV-1 nuclear import inhibitor H27 is a specific HIV-1 capsid-targeting inhibitor that specifically blocks HIV-1 nuclear import, inhibits HIV-1 infection with IC50 of 1.0-2.9  µM in HeLa-R5 and 2.9-5.6  µM in primary lymphocytes.
PC-23743

Elvitegravir

NNRTI

Elvitegravir (JTK-303, GS-9137) is a potent, selective HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) with IC50 of 7.2 nM in 7.2 nM in the strand transfer assay and EC50 of 0.9 nM in acute HIV-1 infection assay.
PC-23582

Dapivirine

NNRTI

Dapivirine (TMC120, R147681) is a potent, HIV-1 nonnucleoside reverse transcriptase inhibitor (NNRTI) with IC50 of 24 nM, inhibits syncytium formation of HIV-1 IIIB-infected CEM T cells with EC50 of 1 nM, shows high activity against wild-type and mutant HIV.
PC-23258

VH3739937

HIV-1 maturation inhibitor

VH3739937 (GSK3739937, VH-937) is a potent, specific HIV-1 maturation inhibitor with EC50 of 1.8 nM against NLRepRlucP373S reporter virus.
PC-23160

DMJ-II-121

HIV-1 inhibitor

DMJ-II-121 is a small molecule inhibitor of HIV-1 envelope glycoprotein gp120, blocks CD4 binding, and inhibits HIV-1 infection.
PC-23159

Compound 484

HIV-1 inhibitor

Compound 484 is a small molecule inhibitor of HIV-1 envelope glycoprotein function that block two CD4-induced conformational changes, exhibits broad range activity against diverse HIV-1 strains.

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