| Cat. No. |
Product Name |
Information |
| PC-45186 |
Atazanavir
HIV-1 protease inhibitor
|
Atazanavir (BMS-232632) is a highly potent HIV-1 protease inhibitor that exhibits potent anti-HIV activity EC50 of 2.6-5.3 nM and EC90 of 9-15 nM in cell culture. |
| PC-42793 |
BMS-538203
|
BMS-538203 is a chemical intermidate of BMS-626529, a HIV-1 attachment inhibitor that targets gp120. |
| PC-27767 |
HIV capsid modulator 5-33d
HIV capsid modulator
|
HIV capsid modulator 5-33d is a potent HIV capsid modulator, exhibits potent antiviral activity with EC50 of 0.14 uM, exhibits potent binding affinities to the CA hexamer with KD of 59.0 nM, but not CA monomer. |
| PC-27428 |
Fexategravir
HIV integrase inhibitor
|
Fexategravir is a potent HIV integrase inhibitor. |
| PC-27150 |
Fangchinoline
CAS 436-77-1
|
Fangchinoline is a natural bisbenzylisoquinoline alkaloid isolated from Stephania tetrandra whtinin extensive biological activities, such as enhancing immunity, anti-inflammatory sterilization and anti-atherosclerosis, inhibits HIV-1 replication by impairing gp160 proteolytic processing, suppresses FAK-mediated signaling pathway in cancer cells which highly expressed FAK, enhances antigen cross-presentation in a DNGR-1 (CLEC9A)-dependent manner. |
| PC-26785 |
TMC-126
HIV protease inhibitor
|
TMC-126 (UIC-94003) is a potent, nonpeptidic human immunodeficiency virus (HIV) protease inhibitor, suppresses a wide spectrum of HIV-1, HIV-2, and various clinical HIV-1 strains with IC50 of 0.3-5.5 nM. |
| PC-26094 |
Ro24-7429
HIV-1 Tat inhibitor, RUNX1 inhibitor
|
Ro24-7429 is a potent, specific and orally active HIV-1 transactivator protein Tat antagonist, is also a runt-related transcription factor 1 (RUNX1) inhibitor. |
| PC-26025 |
Fosamprenavir
HIV-1 protease inhibitor
|
Fosamprenavir (Amprenavir phosphate, GW433908) is the phosphate ester prodrug of the HIV-1 protease inhibitor amprenavir with improved solubility. |
| PC-25848 |
019854-B06
HIV-1 Tat inhibitor
|
019854-B06 is a potent tat-binding antiretroviral compound with IC50 of 1.4 and 0.83 uM in F-Luc activity and HIV-1 infection assays, inhibits Tat-dependent transcription phase, shows binding affinity (KD) of 33.5 uM to Tat peptide. |
| PC-25467 |
Fostemsavir
HIV-1 attachment inhibitor
|
Fostemsavir (BMS-663068) is the phosphonooxymethyl prodrug of Temsavir (BMS-626529), which is a highly potent, small molecule HIV-1 attachment inhibitor, inhibits HIV-1 gp120-directed attachment by preventing gp120 from binding to CD4. |
| PC-25439 |
VH4004280
HIV-1 capsid inhibitor
|
VH4004280 (VH-280) is a highly potent HIV-1 capsid inhibitor with EC50 and EC90 of 0.093 nM and 0.23 nM respectively. |
| PC-25108 |
Cyclotriazadisulfonamide
Sec61 inhibitor
|
Cyclotriazadisulfonamide (CADA) is a specific CD4-targeted HIV entry inhibitor, inhibits the co-translational translocation of human CD4 (huCD4) into the ER lumen in a signal peptide (SP)-dependent, also is a Sec61 translocon inhibitor. |
