| Cat. No. |
Product Name |
Information |
| PC-60408 |
PF-46396
HIV-1 Gag maturation inhibitor
|
PF-46396 is a specific small-molecule inhibitor of HIV-1 Gag maturation that interferes specifically with the cleavage of the CA/SP1 (p25) Gag precursor to the mature CA (p24) protein. |
| PC-60406 |
HIV InSTI-1
HIV integrase inhibitor
|
HIV InSTI-1 is a potent HIV integrase strand transfer inhibitor (InSTIs) with IC50 of 8 nM in HIV replication assay. |
| PC-60405 |
MK-0536
HIV-1 integrase inhibitor
|
MK-0536 is a potent HIV-1 integrase strand transfer inhibitor with IC50 of 33 nM, 9.5 nM, 40 nM, 20 nM and 237 nM for wt IN, IN Y143R, IN N155H, G118R and IN G140S-Q148H, respectively. |
| PC-70011 |
NBD-14107
HIV-1 entry inhibitor
|
NBD-14107 (NBD14107) potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction. |
| PC-70010 |
NBD-11021
gp120-CD4 inhibitor
|
NBD-11021 (NBD11021) is a small molecule, full antagonist of CD4 that blocks gp120-CD4 interaction. |
| PC-45133 |
Saquinavir
HIV-1 protease inhibitor
|
Saquinavir (Ro 31-8959) is a potent and selective inhibitor of HIV-1 protease with IC50 of 0.5-6 nM in cell assays. |
| PC-46011 |
Etravirine
NNRTI
|
Etravirine (R-165335;TMC-125) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) for treatment of HIV-1 infection. |
| PC-45214 |
Zalcitabine
NRTI
|
Zalcitabine (Dideoxycytidin) is a pyrimidine analog reverse transcriptase inhibitor (NRTI) for the treatment of HIV/AIDS. |
| PC-42548 |
Raltegravir
HIV integrase inhibitor
|
Raltegravir (MK-0518) is a potent, selective, orally bioavailable HIV-integrase inhibitor with IC50 of 15 nM. |
| PC-45164 |
Darunavir
HIV-1 protease inhibitor
|
A potent, selective HIV-1 protease inhibitor that is extremely potent against laboratory HIV-1 strains and primary clinical isolates with IC50 of 3 nM, IC90 of 9 nM. |
| PC-45473 |
(±)-BI-D
HIV integrase inhibitor
|
(±)-BI-D is a potent, allosteric HIV integrase inhibitor (Kd=34 nM) that binds the LEDGF/p75 binding site on integrase. |
| PC-45509 |
D77
HIV integrase inhibitor
|
D77 is a potent inhibitor of HIV-1 integrase-LEDGF/p75 interaction binds to IN and IN(T125A) with Kd of 5.81 and 15.2 uM. |
