| Cat. No. |
Product Name |
Information |
| PC-62901 |
YIR-821
CD4 mimic, HIV inhibitor
|
YIR-821 is a small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 2.8 uM against YTA48P virus with no significant cytotoxicity (CC50>200 uM). |
| PC-62899 |
HAR-171
CD4 mimic
|
HAR-171 is a small molecule CD4 mimic and gp120-CD4 blocker that acts as a highly potent HIV entry inhibitor with IC50 of 0.43 uM against YTA48P virus with no significant cytotoxicity (CC50>120 uM). |
| PC-62898 |
YYA-021
gp120-CD4 inhibitor
|
YYA-021 is a small-molecule gp120-CD40 blocker that acts as a highly potent HIV entry inhibitor with IC50 of 9 uM against YTA48P virus with no significant cytotoxicity. |
| PC-62831 |
GSK-8999
HIV-1 maturation inhibitor
|
GSK-8999 (GSK-2578999) is a novel, potent HIV-1 maturation inhibitor with IC50 values of 17 nM, 23 nM, 25 nM, and 8 nM for wild type, Q369H, V370A, and T371A respectively. |
| PC-62712 |
RN-18
|
RN-18 is a small molecule that antagonizes HIV-1 Vif function and inhibits HIV-1 replication only in the presence of A3G. |
| PC-62605 |
GRL-079
HIV-1 protease inhibitor
|
GRL-079 is a novel potent, nonpeptidic HIV-1 protease inhibitor with 2.5-30 nM against wild-type HIV-1NL4-3, 0.3-6.7 nM against HIV-2EHO, and 0.9-90 nM against laboratory-selected-PI-resistant HIV-1 and clinical HIV-1 variants resistant to multiple FDA-approved PIs (HIVMDR). |
| PC-62482 |
BI 224436
HIV-1 integrase inhibitor
|
BI 224436 (BI-224436) is a specific small molecule HIV-1 non-catalytic-site integrase inhibitor (NCINI) with IC50 of 15 nM in LTR 3'-processing assays. |
| PC-62456 |
Nef-IN-B9
Hck inhibitor, Nef inhibitor
|
Nef-IN-B9 (Hck inhibitor B9) is a small molecule that blocks Nef-dependent Hck activity with IC50 of 2.8 uM, while the activity against Hck alone is >20 uM. |
| PC-62359 |
DB213
HIV inhibitor
|
DB213 (RG-501) is a small molecule stimulator of HIV-1 frameshifting and inhibitor of viral replication, causes an imbalance in the ratio of Gag to Gag-Pol, and inhibits viral particle assembly. |
| PC-62258 |
HIV-1 inhibitor 18A
HIV-1 inhibitor
|
HIV-1 inhibitor 18A is a novel broad HIV-1 inhibitor that blocks envelope glycoprotein transitions critical for entry, specifically inhibits the entry of a wide range of HIV-1 isolates with mean IC50 of 6.4 uM. |
| PC-62244 |
LEDGIN6
HIV-1 integrase inhibitor
|
CX 04328 (LEDGIN6) is an allosteric HIV-1 integrase inhibitor that inhibits the LEDGF/p75-integrase interaction with IC50 of 1.37 uM, antiviral activity EC50 of 2.35 uM. |
| PC-62243 |
HIV-1 Integrase Inhibitor 7
HIV-1 integrase inhibitor
|
HIV-1 Integrase Inhibitor 7 is an allosteric HIV-1 integrase inhibitor that inhibits the LEDGF/p75-integrase interaction with IC50 of 0.58 uM, antiviral activity EC50 of 0.76 uM. |
