| Cat. No. |
Product Name |
Information |
| PC-62605 |
GRL-079
HIV-1 protease inhibitor
|
GRL-079 is a novel potent, nonpeptidic HIV-1 protease inhibitor with 2.5-30 nM against wild-type HIV-1NL4-3, 0.3-6.7 nM against HIV-2EHO, and 0.9-90 nM against laboratory-selected-PI-resistant HIV-1 and clinical HIV-1 variants resistant to multiple FDA-approved PIs (HIVMDR). |
| PC-62482 |
BI 224436
HIV-1 integrase inhibitor
|
BI 224436 (BI-224436) is a specific small molecule HIV-1 non-catalytic-site integrase inhibitor (NCINI) with IC50 of 15 nM in LTR 3'-processing assays. |
| PC-62456 |
Nef-IN-B9
Hck inhibitor, Nef inhibitor
|
Nef-IN-B9 (Hck inhibitor B9) is a small molecule that blocks Nef-dependent Hck activity with IC50 of 2.8 uM, while the activity against Hck alone is >20 uM. |
| PC-62359 |
DB213
HIV inhibitor
|
DB213 (RG-501) is a small molecule stimulator of HIV-1 frameshifting and inhibitor of viral replication, causes an imbalance in the ratio of Gag to Gag-Pol, and inhibits viral particle assembly. |
| PC-62244 |
LEDGIN6
HIV-1 integrase inhibitor
|
CX 04328 (LEDGIN6) is an allosteric HIV-1 integrase inhibitor that inhibits the LEDGF/p75-integrase interaction with IC50 of 1.37 uM, antiviral activity EC50 of 2.35 uM. |
| PC-62191 |
SAMT-247
HIV-1 NCp7 inhibitor
|
SAMT-247 is a potent HIV-1 nucleocapsid protein NCp7 inhibitor with EC50 of 0.6 uM with low cellular toxicity (TC50>100 uM) in cultured and primary cells. |
| PC-61948 |
YLC2-155
HIV-1 reverse transcriptase inhibitor
|
YLC2-155 is a novel potent HIV-1 reverse transcriptase (RT) inhibitor that inhibits both polymerase (IC50=2.6 uM) and RNase H function (IC50=0.65 uM) of RT. |
| PC-61944 |
Bictegravir
HIV-1 integrase inhibitor
|
Bictegravir (GS9883) is a potent HIV-1 integrase (IN) that specifically targets IN strand transfer activity with IC50 of 7.5 nM. |
| PC-61914 |
MUT-A
HIV-1 integrase-LEDGF allosteric inhibitor
|
MUT-A is a novel potent, HIV-1 Integrase IN-LEDGF allosteric inhibitor, shows potent anti-HIV activity with EC50 of 32 nM and 12 nM for NL4-3 or HxB2 HIV-1 strains, respectively. |
| PC-61885 |
PF-4776548
HIV integrase inhibitor
|
PF-4776548 (PF-04776548) novel HIV integrase inhibitor for treatment of HIV infections.. |
| PC-61817 |
MK-8591
HIV-1 RT inhibitor
|
MK-8591 (Islatravir, MK8591, EFdA) is a nucleoside analog that exhibits remarkable potency against wild-type and drug-resistant HIVs, inhibits HIV-1 reverse transcriptase with multiple mechanisms. |
| PC-61518 |
Vipirinin
HIV-1 Vpr inhibitor
|
A coumarin-based HIV-1 viral protein R (Vpr) inhibitor, inhibits Vpr-dependent viral infection of human macrophages. |
