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Cat. No. Product Name Information
PC-62901

YIR-821

CD4 mimic, HIV inhibitor

YIR-821 is a small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 2.8 uM against YTA48P virus with no significant cytotoxicity (CC50>200 uM).
PC-62899

HAR-171

CD4 mimic

HAR-171 is a small molecule CD4 mimic and gp120-CD4 blocker that acts as a highly potent HIV entry inhibitor with IC50 of 0.43 uM against YTA48P virus with no significant cytotoxicity (CC50>120 uM).
PC-62898

YYA-021

gp120-CD4 inhibitor

YYA-021 is a small-molecule gp120-CD40 blocker that acts as a highly potent HIV entry inhibitor with IC50 of 9 uM against YTA48P virus with no significant cytotoxicity.
PC-62831

GSK-8999

HIV-1 maturation inhibitor

GSK-8999 (GSK-2578999) is a novel, potent HIV-1 maturation inhibitor with IC50 values of 17 nM, 23 nM, 25 nM, and 8 nM for wild type, Q369H, V370A, and T371A respectively.
PC-62712

RN-18

RN-18 is a small molecule that antagonizes HIV-1 Vif function and inhibits HIV-1 replication only in the presence of A3G.
PC-62605

GRL-079

HIV-1 protease inhibitor

GRL-079 is a novel potent, nonpeptidic HIV-1 protease inhibitor with 2.5-30 nM against wild-type HIV-1NL4-3, 0.3-6.7 nM against HIV-2EHO, and 0.9-90 nM against laboratory-selected-PI-resistant HIV-1 and clinical HIV-1 variants resistant to multiple FDA-approved PIs (HIVMDR).
PC-62482

BI 224436

HIV-1 integrase inhibitor

BI 224436 (BI-224436) is a specific small molecule HIV-1 non-catalytic-site integrase inhibitor (NCINI) with IC50 of 15 nM in LTR 3'-processing assays.
PC-62456

Nef-IN-B9

Hck inhibitor, Nef inhibitor

Nef-IN-B9 (Hck inhibitor B9) is a small molecule that blocks Nef-dependent Hck activity with IC50 of 2.8 uM, while the activity against Hck alone is >20 uM.
PC-62359

DB213

HIV inhibitor

DB213 (RG-501) is a small molecule stimulator of HIV-1 frameshifting and inhibitor of viral replication, causes an imbalance in the ratio of Gag to Gag-Pol, and inhibits viral particle assembly.
PC-62258

HIV-1 inhibitor 18A

HIV-1 inhibitor

HIV-1 inhibitor 18A is a novel broad HIV-1 inhibitor that blocks envelope glycoprotein transitions critical for entry, specifically inhibits the entry of a wide range of HIV-1 isolates with mean IC50 of 6.4 uM.
PC-62244

LEDGIN6

HIV-1 integrase inhibitor

CX 04328 (LEDGIN6) is an allosteric HIV-1 integrase inhibitor that inhibits the LEDGF/p75-integrase interaction with IC50 of 1.37 uM, antiviral activity EC50 of 2.35 uM.
PC-62243

HIV-1 Integrase Inhibitor 7

HIV-1 integrase inhibitor

HIV-1 Integrase Inhibitor 7 is an allosteric HIV-1 integrase inhibitor that inhibits the LEDGF/p75-integrase interaction with IC50 of 0.58 uM, antiviral activity EC50 of 0.76 uM.

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