| Cat. No. |
Product Name |
Information |
| PC-70242 |
L-870810
HIV integrase inhibitor
|
A potent, selective inhibitor of HIV integrase (IC50=8-15 nM) with potent antiviral activity in cell culture and good pharmacokinetic properties. |
| PC-70236 |
SCH 350581
CCR5 inhibitor
|
SCH 350581 (AD-101) is a specific small molecule inhibitor of CCR5, inhibits HIV-1 entry. |
| PC-70235 |
SCH 351125
HIV-1 entry inhibitor
|
SCH 351125 (Ancriviroc) is a small molecule inhibitor of HIV-1 entry via the CCR5 coreceptor. |
| PC-70320 |
DMJ-I-228
gp120-CD4 inhibitor
|
DMJ-I-228 is a small molecule CD4-mimetic that binds gp120 and blocks CD4 binding, inhibits HIV-1 entry with IC50 of 86.9 uM. |
| PC-70319 |
JP-III-48
gp120-CD4 inhibitor
|
JP-III-48 is a small molecule CD4-mimetic that binds gp120 and blocks CD4 binding, inhibits HIV-1 entry. |
| PC-70309 |
DDX3-IN-16d
DDX3 inhibitor
|
DDX3-IN-16d is a small molecule inhibitor (IC50=0.3 uM) of DEAD-box polypeptide 3 (DDX3), a human host factor required for the replication of several DNA and RNA viruses. |
| PC-61164 |
BMS-986001
NRTI
|
A thymidine analogue nucleoside reverse transcriptase inhibitor (NRTI) that inhibits HIV-2 isolates from treatment-naive individuals with EC50 of 30-81 nM. |
| PC-60887 |
N.41
HIV-1 Vif inhibitor
|
N.41 (HIV inhibitor N.41, Vif inhibitor N.41) is a novel HIV-1 inhibitor targeting Vif-dependent degradation of human APOBEC3G (A3G) protein (IC50=2.2 uM). |
| PC-60510 |
Elsulfavirine
NNRTI
|
Elsulfavirine (R-1206) is a new-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) for the treatment of HIV-1 infections, the prodrug of the active compound VM-1500A. |
| PC-60468 |
IDX899
NNRTI
|
IDX899 (Fosdevirine, GSK 2248761) is a novel potent, selective HIV non-nucleoside reverse transcriptase inhibitor (NNRTI) with EC50 of 1, 1.3, 2.8 and 11 nM for WT, K103N, Y181C and K103N/Y181C, respectively. |
| PC-60408 |
PF-46396
HIV-1 Gag maturation inhibitor
|
PF-46396 is a specific small-molecule inhibitor of HIV-1 Gag maturation that interferes specifically with the cleavage of the CA/SP1 (p25) Gag precursor to the mature CA (p24) protein. |
| PC-60406 |
HIV InSTI-1
HIV integrase inhibitor
|
HIV InSTI-1 is a potent HIV integrase strand transfer inhibitor (InSTIs) with IC50 of 8 nM in HIV replication assay. |
