| Cat. No. |
Product Name |
Information |
| PC-28138 |
GD136
H1R/H4R antagonist
|
GD136 (GD-136) is a potent, selective dual histamine H1 and H4 receptors (H1R/H4R) ligand / antagonist with pKi of 7.61 and 7.93 (hH1R/hH4R), shows >100-fold selectivity over hH2R and hH3R. |
| PC-28137 |
Olopatadine hydrochloride
H1R antagonist
|
Olopatadine hydrochloride (AL-4943A, KW-4679) is an antiallergic/antihistaminic agent that inhibits mast cell mediator release and possesses histamine H1 receptor (H1R) antagonist activity with Ki of 31.6 nM, shows much lower affinities for H2 receptors and H3 receptors (Ki>50 uM). |
| PC-28136 |
Olopatadine
H1R antagonist
|
Olopatadine (AL-4943A, KW-4679) is an antiallergic/antihistaminic agent that inhibits mast cell mediator release and possesses histamine H1 receptor (H1R) antagonist activity with Ki of 31.6 nM, shows much lower affinities for H2 receptors and H3 receptors (Ki>50 uM). |
| PC-28131 |
Adriforant hydrochloride
Histamine H4 antagonist
|
Adriforant hydrochloride (PF-3893787, ZPL-3893787) is a potent and selective histamine H4 receptor (H4R) antagonist with binding Ki of 2.4 nM. |
| PC-28130 |
GD134
H1R/H4R antagonist
|
GD134 (GD-134) is a potent, selective dual histamine H1 and H4 receptors (H1R/H4R) ligand / antagonist with pKi of 7.54 and 7.67 (hH1R/hH4R), shows 5-fold selectivity over hH3R and high selectivity over hH2R. |
| PC-23473 |
JNJ-7777120
H4R antagonist
|
JNJ-7777120 (JNJ 7777120) is potent and selective histamine H4 receptor (H4R) antagonist with Ki of 4.5 nM (hH4R), >1000-fold selectivity over H1, H2, or H3 receptors. |
| PC-20926 |
JNJ 10191584
H4R antagonist
|
JNJ 10191584 (VUF6002) is a potent, highly selective, orally active histamine H(4) receptor antagonist with binding Ki of 26 nM, 540-fold selectivity to H4 receptor over H3 receptor. |
| PC-20925 |
JNJ 10191584 maleate
Histamine H4 antagonist
|
JNJ-10191584 (VUF6002) maleate is a potent, highly selective, orally active histamine H(4) receptor antagonist with binding Ki of 26 nM, 540-fold selectivity to H4 receptor over H3 receptor. |
| PC-49738 |
UR-MB-69
H2 receptor agonist
|
UR-MB-69 is a potent agonist of histamine H2 receptor (H2R) dopamine receptor D3R with pKi of 8.69 and 8.06, respectively. |
| PC-49737 |
UR-MB-158
H2 receptor agonist
|
UR-MB-158 is a a potent, selective H2 receptor agonist. |
| PC-49736 |
UR-Po563
H2 receptor agonist
|
UR-Po563 is a potent, selective H2 receptor agonist with pKi of 7.75, >400-fold selectivity over H1R/H3R/H4R. |
| PC-47094 |
RGH-235
H3R antagonist
|
RGH-235 is a potent, selective, and orally active H3 receptor antagonist/inverse agonist with high affinity (Ki=3.0-9.2 nM, depending on species), without affinity to H1, H2 or H4 receptors. |
