| Cat. No. |
Product Name |
Information |
| PC-20688 |
MMRi71
MDM2-MDM4 E3 ligase inhibitor
|
MMRi71 is a small molecule inhibitor of the E3 ligase activity of MDM2-MDM4, and an inducer of MDM4 and FTH1 dual protein degradation and p53-independent apoptosis in leukemia cells. |
| PC-20687 |
MMRi67
MDM2-MDM4 E3 ligase inhibitor
|
MMRi67 is a potent E3 ligase inhibitor of the MDM2-MDM4 E3 complex, inhibits RING-RING interaction of MDM4 and MDM2B with Kd of 896 nM. |
| PC-62080 |
RETRA hydrochloride
|
RETRA hydrochloride is a small molecule mutant p53 reactivator that activates a set of p53-regulated genes and specifically suppresses mutant p53-bearing tumor cells in vitro and in mouse xenograft. |
| PC-62079 |
RETRA hydrobromide
|
RETRA hydrobromide is a small molecule mutant p53 reactivator that activates a set of p53-regulated genes and specifically suppresses mutant p53-bearing tumor cells in vitro and in mouse xenograft. |