Cat. No. |
Product Name |
Information |
PC-49512 |
GY1-22
DNAJA1-mutp53R175H inhibitor
|
GY1-22 is a small molecule inhibitor against DNAJA1-mutP53R175H interacting pocket, reduces mutp53 protein expression in colon cancer cell line with p53R175H mutation. |
PC-62080 |
RETRA hydrochloride
|
RETRA hydrochloride is a small molecule mutant p53 reactivator that activates a set of p53-regulated genes and specifically suppresses mutant p53-bearing tumor cells in vitro and in mouse xenograft. |
PC-62079 |
RETRA hydrobromide
|
RETRA hydrobromide is a small molecule mutant p53 reactivator that activates a set of p53-regulated genes and specifically suppresses mutant p53-bearing tumor cells in vitro and in mouse xenograft. |
PC-60262 |
MK-8242
|
A potent, orally bioavailable, small-molecule inhibitor of HDM2/p53 protein-protein interaction. |