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Cat. No. Product Name Information
PC-49512

GY1-22

DNAJA1-mutp53R175H inhibitor

GY1-22 is a small molecule inhibitor against DNAJA1-mutP53R175H interacting pocket, reduces mutp53 protein expression in colon cancer cell line with p53R175H mutation.
PC-62080

RETRA hydrochloride

RETRA hydrochloride is a small molecule mutant p53 reactivator that activates a set of p53-regulated genes and specifically suppresses mutant p53-bearing tumor cells in vitro and in mouse xenograft.
PC-62079

RETRA hydrobromide

RETRA hydrobromide is a small molecule mutant p53 reactivator that activates a set of p53-regulated genes and specifically suppresses mutant p53-bearing tumor cells in vitro and in mouse xenograft.
PC-60262

MK-8242

A potent, orally bioavailable, small-molecule inhibitor of HDM2/p53 protein-protein interaction.

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