| Cat. No. |
Product Name |
Information |
| PC-45239 |
Vinblastine
Microtubule inhibitor
|
Vinblastine is a cytotoxic alkaloid that binds tubulin and inhibits the assembly of microtubules, a chemotherapy agent for treatment of a number of types of cancer. |
| PC-45151 |
Epothilone B
Microtubule stabilizer
|
Epothilone B (EPO-906, Patupilone) blood-brain barrier-permeable microtubule-stabilizing agent that promotes tubulin polymerization and induces G2-M cell cycle arrest with EC50 of 32 nM in HeLa cells. |
| PC-23470 |
Gatorbulin-1
Tubulin inhibitor
|
Gatorbulin-1 (GB1) is a microtubule-destabilizing cyclodepsipeptide, directly inhibits tubulin polymerization in vitro in an iron-independent manner. |
| PC-23206 |
Lisavanbulin dihydrochloride
Tubulin inhibitor
|
Lisavanbulin dihydrochloride (BAL101553) is a microtubule-destabilizing drug, binds to the colchicine site of tubulin, is the prodrug of the microtubule targeting agent Avanbulin (BAL27862). |
| PC-23205 |
Lisavanbulin
Tubulin inhibitor
|
Lisavanbulin (BAL101553) is a microtubule-destabilizing drug, binds to the colchicine site of tubulin, is the prodrug of the microtubule targeting agent Avanbulin (BAL27862). |
| PC-23110 |
BNZ-111
Tubulin inhibitor
|
BNZ-111 is a novel reversible tubulin inhibitor, binds the β subunit of curved tubulin, possesses potent anticancer activities to various cancer cell lines. |
| PC-22895 |
MI-181
M-phase inhibitor
|
MI-181 (Mitotic inhibitor-181) is a potent M-phase inhibitor with mitotic arrest IC50 of 23 nM and cell death IC50 of 17 nM, inhibits tubulin polymerization and modulates cilia length and biogenesis. |
| PC-22871 |
Vinblastine sulfate
Microtubule inhibitor
|
Vinblastine sulfate is a cytotoxic alkaloid that binds tubulin and inhibits the assembly of microtubules, a chemotherapy agent for treatment of a number of types of cancer. |
| PC-22831 |
PTA-1
Tubulin polymerization inhibitor
|
PTA-1 is a potent anticancer compound, disturbs microtubule organization and inhibits tubulin polymerization, shows cytotoxicity to various cancer cells (MCF-7, CC50=0.23 uM), induces apoptosis and cell cycle arrest. |
| PC-22650 |
Plecstatin-1 hydrochloride
Plectin inhibitor
|
Plecstatin-1 hydrochloride is a specific ruthenium(arene) pyridinecarbothioamide targeting plectin, affects cytoarchitecture and shape of keratinocytes, inhibits tumor invasiveness. |
| PC-22649 |
Plecstatin-1
Plectin inhibitor
|
Plecstatin-1 is a specific ruthenium(arene) pyridinecarbothioamide targeting plectin, affects cytoarchitecture and shape of keratinocytes, inhibits tumor invasiveness. |
| PC-21448 |
TN-2
Tubulin/NRP1 inhibitor
|
TN-2 is a potent, dual tubulin/NRP1-targeting inhibitor with IC50 of 0.71 uM (tubulin polymerization) and 0.85 uM (NRP-1), inhibits proliferation and angiogenesis of tumor cells. |
