| Cat. No. |
Product Name |
Information |
| PC-21390 |
Plinabulin
Tubulin inhibitor
|
Plinabulin (NPI-2358) is a small molecule vascular disrupting agent against tubulin-depolymerizing, shows IC50 of 9.8 nM against HT-29 cells. |
| PC-21389 |
BNC105
Tubulin inhibitor
|
BNC105 is a small molecule tubulin polymerization inhibitor (IC50=3.0 uM) with potent antiproliferative and tumor vascular disrupting properties. |
| PC-21388 |
KGP618
Tubulin inhibitor
|
KGP618 is the phosphate prodrug salt of KGP591, which is a small molecule inhibitor of tubulin polymerization with IC50 of 0.57 uM. |
| PC-21387 |
KGP591
Tubulin inhibitor
|
KGP591 is a small molecule inhibitor of tubulin polymerization with IC50 of 0.57 uM, exhibits cytotoxicity against the MCF-7 and MDA-MB-231 human breast cancer cell lines with GI50 of 320 and 102 nM, respectively. |
| PC-20928 |
Epothilone A
Tubulin inhibitor
|
Epothilone A (Epo A) is a competitive inhibitor of the binding of [3H] paclitaxel to tubulin polymers with Ki of 0.6-1.4 uM. |
| PC-20673 |
EAPB02303
Microtubule inhibitor
|
EAPB02303 (EAPB 02303) is a novel microtubule-disrupting agent with in-vivo activity in PDAC and in-vitro synergy with Paclitaxel, inhibits A375 melanoma cell line with IC50 of 3 nM. |
