Microtubule/Tubulin compound (inhibitors, antagonists, modulators)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-21448	TN-2 Tubulin/NRP1 inhibitor	TN-2 is a potent, dual tubulin/NRP1-targeting inhibitor with IC50 of 0.71 uM (tubulin polymerization) and 0.85 uM (NRP-1), inhibits proliferation and angiogenesis of tumor cells.
PC-21390	Plinabulin Tubulin inhibitor	Plinabulin (NPI-2358) is a small molecule vascular disrupting agent against tubulin-depolymerizing, shows IC50 of 9.8 nM against HT-29 cells.
PC-21389	BNC105 Tubulin inhibitor	BNC105 is a small molecule tubulin polymerization inhibitor (IC50=3.0 uM) with potent antiproliferative and tumor vascular disrupting properties.
PC-21388	KGP618 Tubulin inhibitor	KGP618 is the phosphate prodrug salt of KGP591, which is a small molecule inhibitor of tubulin polymerization with IC50 of 0.57 uM.
PC-21387	KGP591 Tubulin inhibitor	KGP591 is a small molecule inhibitor of tubulin polymerization with IC50 of 0.57 uM, exhibits cytotoxicity against the MCF-7 and MDA-MB-231 human breast cancer cell lines with GI50 of 320 and 102 nM, respectively.
PC-20928	Epothilone A Tubulin inhibitor	Epothilone A (Epo A) is a competitive inhibitor of the binding of [3H] paclitaxel to tubulin polymers with Ki of 0.6-1.4 uM.
PC-20673	EAPB02303 Microtubule inhibitor	EAPB02303 (EAPB 02303) is a novel microtubule-disrupting agent with in-vivo activity in PDAC and in-vitro synergy with Paclitaxel, inhibits A375 melanoma cell line with IC50 of 3 nM.

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