| Cat. No. |
Product Name |
Information |
| PC-22871 |
Vinblastine sulfate
Microtubule inhibitor
|
Vinblastine sulfate is a cytotoxic alkaloid that binds tubulin and inhibits the assembly of microtubules, a chemotherapy agent for treatment of a number of types of cancer. |
| PC-22831 |
PTA-1
Tubulin polymerization inhibitor
|
PTA-1 is a potent anticancer compound, disturbs microtubule organization and inhibits tubulin polymerization, shows cytotoxicity to various cancer cells (MCF-7, CC50=0.23 uM), induces apoptosis and cell cycle arrest. |
| PC-22650 |
Plecstatin-1 hydrochloride
Plectin inhibitor
|
Plecstatin-1 hydrochloride is a specific ruthenium(arene) pyridinecarbothioamide targeting plectin, affects cytoarchitecture and shape of keratinocytes, inhibits tumor invasiveness. |
| PC-22649 |
Plecstatin-1
Plectin inhibitor
|
Plecstatin-1 is a specific ruthenium(arene) pyridinecarbothioamide targeting plectin, affects cytoarchitecture and shape of keratinocytes, inhibits tumor invasiveness. |
| PC-21448 |
TN-2
Tubulin/NRP1 inhibitor
|
TN-2 is a potent, dual tubulin/NRP1-targeting inhibitor with IC50 of 0.71 uM (tubulin polymerization) and 0.85 uM (NRP-1), inhibits proliferation and angiogenesis of tumor cells. |
| PC-21389 |
BNC105
Tubulin inhibitor
|
BNC105 is a small molecule tubulin polymerization inhibitor (IC50=3.0 uM) with potent antiproliferative and tumor vascular disrupting properties. |
| PC-21388 |
KGP618
Tubulin inhibitor
|
KGP618 is the phosphate prodrug salt of KGP591, which is a small molecule inhibitor of tubulin polymerization with IC50 of 0.57 uM. |
| PC-21387 |
KGP591
Tubulin inhibitor
|
KGP591 is a small molecule inhibitor of tubulin polymerization with IC50 of 0.57 uM, exhibits cytotoxicity against the MCF-7 and MDA-MB-231 human breast cancer cell lines with GI50 of 320 and 102 nM, respectively. |
| PC-20928 |
Epothilone A
Tubulin inhibitor
|
Epothilone A (Epo A) is a competitive inhibitor of the binding of [3H] paclitaxel to tubulin polymers with Ki of 0.6-1.4 uM. |
| PC-20673 |
EAPB02303
Microtubule inhibitor
|
EAPB02303 (EAPB 02303) is a novel microtubule-disrupting agent with in-vivo activity in PDAC and in-vitro synergy with Paclitaxel, inhibits A375 melanoma cell line with IC50 of 3 nM. |
