| Cat. No. |
Product Name |
Information |
| PC-60870 |
NSC-639829
Tubulin inhibitor
|
NSC-639829 is a potent anticancer agent that demonstrates potent antitumor activity in vitro against several cancer cell lines as well as in vivo against several tumor models, effectively inhibits in vitro tubulin polymerization. |
| PC-60807 |
DJ101
Tubulin inhibitor
|
A novel potent and metabolically stable tubulin inhibitor that can circumvent the drug efflux pumps responsible for multidrug resistance of existing tubulin inhibitors. |
| PC-60561 |
PBOX-15
Microtubule inhibitor
|
PBOX-15 is a microtubule targeting agent that induces apoptosis, upregulates death receptors, and potentiates TRAIL-mediated apoptosis in multiple cancer cells. |
| PC-60553 |
MPT0B002
Microtubule inhibitor
|
MPT0B002 is a novel microtubule inhibitor, downregulates T315I mutant Bcr-Abl and induces apoptosis of imatinib-resistant chronic myeloid leukemia cells. |
| PC-70178 |
Ombrabulin
Tubulin inhibitor
|
Ombrabulin (AVE8062) is a combretastatin A-4 derivative and tubulin polymerization inhibitor that strongly stanches tumour blood flows and inhibits growth of tumours developing in various tissues and organ.. |
| PC-60252 |
STK899704
Tubulin inhibitor
|
STK899704 is a novel tubulin inhibitor that inhibits the proliferation of cancer cell lines with IC50 of 0.2-1.0 uM. |
| PC-42620 |
Lexibulin dihydrochloride
|
An orally active tubulin polymerization inhibitor with potent cytotoxic and vascular disrupting activity in vitro and in vivo. |
| PC-42619 |
Lexibulin
Tubulin inhibitor
|
Lexibulin (CYT997) is an orally active tubulin polymerization inhibitor with potent cytotoxic and vascular disrupting activity in vitro and in vivo. |
| PC-45982 |
Cephalomannine
Microtubule stabilizer
|
Cephalomannine is taxol derivative with antitumor, antiproliferative properties, is active in promoting microtubule assembly. |
| PC-42466 |
Ixabepilone
Microtubule stabilizer, TUBB3 inhibitor
|
Ixabepilone (Azaepothilone B, BMS-247550) is a semisynthetic Epothilone B analogue and potent, orally active microtubule stabilizer, also is a TUBB3 inhibitor. |
| PC-45256 |
4-Demethylepipodophyllotoxin
Microtubule inhibitor
|
4'-Demethylepipodophyllotoxin (4'-DMEP) is a potent inhibitor of microtubule assembly, and a key intermediate compound for the preparation of podophyllotoxin-type anti-cancer compounds. |
| PC-45268 |
Fosbretabulin disodium
Microtubule inhibitor
|
Fosbretabulin disodium (CA4DP, Combretastatin A-4) is a derivative of combretastatin that acts as a microtubule destabilising agent, damages the vasculature (blood vessels) of cancer tumours causing central necrosis. |
