| Cat. No. |
Product Name |
Information |
| PC-62426 |
SMIFH2
Formin inhibitor
|
SMIFH2 is a small molecule formin homology 2 domains inhibitor of formin-mediated actin assembly, targets formins from evolutionarily diverse organisms including yeast, nematode worm, and mice with IC50s of 5-15 uM. |
| PC-61251 |
STX3451
Microtubule inhibitor
|
STX3451 is a non-steroidal sulphamate analogue of 2-methoxyoestradiol (2ME2) and microtubule disruptor, shows anti-proliferative activity against NCI 60 cell lines with mean GI50 of 50 nM. |
| PC-61247 |
Cabazitaxel
Microtubule inhibitor
|
Cabazitaxel (XRP6258) is a semi-synthetic taxane and microtubule inhibitor for the treatment of hormone-refractory prostate cancer. |
| PC-60910 |
MPT0B098
Microtubule inhibitor, HIF-1α inhibitor
|
MPT0B098 is a potent microtubule inhibitor that not only inhibits the expression levels of HIF-1α protein but also destabilizes HIF-1α mRNA. |
| PC-50006 |
BRD70326
Tubulin inhibitor
|
BRD70326 is a small molecule that inhibits tubulin polymerization. |
| PC-60870 |
NSC-639829
Tubulin inhibitor
|
NSC-639829 is a potent anticancer agent that demonstrates potent antitumor activity in vitro against several cancer cell lines as well as in vivo against several tumor models, effectively inhibits in vitro tubulin polymerization. |
| PC-60807 |
DJ101
Tubulin inhibitor
|
A novel potent and metabolically stable tubulin inhibitor that can circumvent the drug efflux pumps responsible for multidrug resistance of existing tubulin inhibitors. |
| PC-60561 |
PBOX-15
Microtubule inhibitor
|
PBOX-15 is a microtubule targeting agent that induces apoptosis, upregulates death receptors, and potentiates TRAIL-mediated apoptosis in multiple cancer cells. |
| PC-60553 |
MPT0B002
Microtubule inhibitor
|
MPT0B002 is a novel microtubule inhibitor, downregulates T315I mutant Bcr-Abl and induces apoptosis of imatinib-resistant chronic myeloid leukemia cells. |
| PC-70178 |
Ombrabulin
Tubulin inhibitor
|
Ombrabulin (AVE8062) is a combretastatin A-4 derivative and tubulin polymerization inhibitor that strongly stanches tumour blood flows and inhibits growth of tumours developing in various tissues and organ.. |
| PC-60252 |
STK899704
Tubulin inhibitor
|
STK899704 is a novel tubulin inhibitor that inhibits the proliferation of cancer cell lines with IC50 of 0.2-1.0 uM. |
| PC-42620 |
Lexibulin dihydrochloride
|
An orally active tubulin polymerization inhibitor with potent cytotoxic and vascular disrupting activity in vitro and in vivo. |
