| Cat. No. |
Product Name |
Information |
| PC-35597 |
VERU-111
Tubulin inhibitor
|
VERU-111 (Sabizabulin, VERU111) is an oral cytoskeleton disruptor that targets and inhibits microtubules to disrupt androgen receptor transport into the nucleus, shows broad antiviral activity by disrupting the intracellular transport of viruses such as SARS CoV-2. |
| PC-43537 |
Eribulin mesylate
Tubulin inhibitor
|
Eribulin mesylate (B1939, E7389, ER-086526) is a macrocyclic ketone analogue of halichondrir B, shows sub-nM growth inhibitory activities in vitro against numerous human cancer cell lines via inhibition of tubulin polymerization. |
| PC-43536 |
Eribulin
Tubulin inhibitor
|
Eribulin (B1939, E7389, ER-086526) is a macrocyclic ketone analogue of halichondrir B, shows sub-nM growth inhibitory activities in vitro against numerous human cancer cell lines via inhibition of tubulin polymerization. |
| PC-35472 |
Valecobulin
Tubulin inhibitor
|
CKD-516 (Valecobulin, CKD516) is a potent beta-tubulin polymerization inhibitor with marked antitumor activity both in vitro and in vivo. |
| PC-35334 |
Plocabulin
Tubulin inhibitor
|
Plocabulin (PM060184) is a novel tubulin-binding agent binding to αβ-tubulin dimer with nanomolar affinity, inhibits a panel of 23 tumor cell lines with GI50 of 20 pM-5 nM. |
| PC-35304 |
DZ-2384
Tubulin inhibitor
|
DZ-2384 (DZ2384) is a microtubule-targeting agent, exhibits potent antitumor activity in models of multiple cancer types. |
| PC-43449 |
ABT-751
Tubulin inhibitor
|
ABT-751 (E7010) is an orally active antimitotic agent that inhibits tubulin polymerization, exhibits consistent growth-inhibitory activities against a panel of human tumor cell lines (IC50=0.06-0.8 ug/mL). |
| PC-63320 |
FiVe1
Vimentin inhibitor
|
FiVe1 is a vimentin binding small molecule that promotes vimentin disorganization and phosphorylation during metaphase, causes mitotic catastrophe, multinucleation, and the loss of stemness in cancer cells. |
| PC-42867 |
Vinorelbine ditartrate
Tubulin inhibitor
|
Vinorelbine (KW-2307) is a vinca alkaloid chemotherapy agent that inhibits cancer cell mitosis through interaction with tubulin, inhibits HeLa cell proliferation with IC50 of 1.25 nM. |
| PC-42866 |
Vinorelbine
Tubulin inhibitor
|
Vinorelbine (KW-2307) is a vinca alkaloid chemotherapy agent that inhibits cancer cell mitosis through interaction with tubulin, inhibits HeLa cell proliferation with IC50 of 1.25 nM. |
| PC-62674 |
PST-1
Microtubule inhibitor
|
PST-1 is a photoswitchable inhibitor of microtubule with EC50 of 0.5 uM under 390 nm irradiation in the MDA-MB-231 human breast cancer cell lines, 100-fold more cytotoxic than in the dark. |
| PC-62673 |
PST-1P
Microtubule inhibitor
|
PST-1P is a photoswitchable inhibitor of microtubule with EC50 of 0.7 uM under 390 nm irradiation in the MDA-MB-231 human breast cancer cell lines. |
