| Cat. No. |
Product Name |
Information |
| PC-35304 |
DZ-2384
Tubulin inhibitor
|
DZ-2384 (DZ2384) is a microtubule-targeting agent, exhibits potent antitumor activity in models of multiple cancer types. |
| PC-43449 |
ABT-751
Tubulin inhibitor
|
ABT-751 (E7010) is an orally active antimitotic agent that inhibits tubulin polymerization, exhibits consistent growth-inhibitory activities against a panel of human tumor cell lines (IC50=0.06-0.8 ug/mL). |
| PC-63320 |
FiVe1
Vimentin inhibitor
|
FiVe1 is a vimentin binding small molecule that promotes vimentin disorganization and phosphorylation during metaphase, causes mitotic catastrophe, multinucleation, and the loss of stemness in cancer cells. |
| PC-42867 |
Vinorelbine ditartrate
Tubulin inhibitor
|
Vinorelbine (KW-2307) is a vinca alkaloid chemotherapy agent that inhibits cancer cell mitosis through interaction with tubulin, inhibits HeLa cell proliferation with IC50 of 1.25 nM. |
| PC-42866 |
Vinorelbine
Tubulin inhibitor
|
Vinorelbine (KW-2307) is a vinca alkaloid chemotherapy agent that inhibits cancer cell mitosis through interaction with tubulin, inhibits HeLa cell proliferation with IC50 of 1.25 nM. |
| PC-62674 |
PST-1
Microtubule inhibitor
|
PST-1 is a photoswitchable inhibitor of microtubule with EC50 of 0.5 uM under 390 nm irradiation in the MDA-MB-231 human breast cancer cell lines, 100-fold more cytotoxic than in the dark. |
| PC-62673 |
PST-1P
Microtubule inhibitor
|
PST-1P is a photoswitchable inhibitor of microtubule with EC50 of 0.7 uM under 390 nm irradiation in the MDA-MB-231 human breast cancer cell lines. |
| PC-62426 |
SMIFH2
Formin inhibitor
|
SMIFH2 is a small molecule formin homology 2 domains inhibitor of formin-mediated actin assembly, targets formins from evolutionarily diverse organisms including yeast, nematode worm, and mice with IC50s of 5-15 uM. |
| PC-61251 |
STX3451
Microtubule inhibitor
|
STX3451 is a non-steroidal sulphamate analogue of 2-methoxyoestradiol (2ME2) and microtubule disruptor, shows anti-proliferative activity against NCI 60 cell lines with mean GI50 of 50 nM. |
| PC-61247 |
Cabazitaxel
Microtubule inhibitor
|
Cabazitaxel (XRP6258) is a semi-synthetic taxane and microtubule inhibitor for the treatment of hormone-refractory prostate cancer. |
| PC-60910 |
MPT0B098
Microtubule inhibitor, HIF-1α inhibitor
|
MPT0B098 is a potent microtubule inhibitor that not only inhibits the expression levels of HIF-1α protein but also destabilizes HIF-1α mRNA. |
| PC-50006 |
BRD70326
Tubulin inhibitor
|
BRD70326 is a small molecule that inhibits tubulin polymerization. |
